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- W2080534756 abstract "Many poxvirus-encoded virulence factors have been identified as proteins that are secreted from infected cells. The major secreted protein (37 kilodaltons) from cells infected with myxoma virus is encoded by the M-T7 open reading frame. This protein has significant sequence similarity to the human and mouse receptors for interferon-gamma (IFN-gamma). Furthermore, the myxoma M-T7 protein specifically binds rabbit IFN-gamma and inhibits the biological activity of extracellular IFN-gamma, one of the key regulatory cytokines in the host immune response against viral infections." @default.
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- W2080534756 date "1992-11-20" @default.
- W2080534756 modified "2023-09-28" @default.
- W2080534756 title "Encoding of a Homolog of the IFN-γ Receptor by Myxoma Virus" @default.
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- W2080534756 doi "https://doi.org/10.1126/science.1455233" @default.
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