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• W2080541206 abstract "A survey of papers using auditory evoked potentials (AEPs) published over the last 10years (Table I) demonstrates that most AEP studies in animals have used subjective methods for auditory threshold determination. Subjective methods greatly reduce the value of statistical hypothesis testing and jeopardize tests of hypothetical experimental group differences in hearing sensitivity. Correspondingly, many attempts have been made to develop objective threshold determination methods, but these have not been used widely. Further, they seldom include an appreciation of the effects of residual noise in the AEP. In this study, AEPs evoked by tonal and noise stimuli in goldfish (Carassius auratus) were recorded and the residual background noise was measured and analyzed in detail. High variability was found in residual noise, but can be effectively controlled with a simple modification of averaging routines. Considerable interobserver disagreements were found using subjective threshold estimation. An objective method of threshold determination was developed based on comparison between AEP amplitude and controlled residual noise, using a signal detection theory approach to set specific threshold criteria. The usefulness of AEP in hypothesis testing for auditory function requires more control over residual background noise amplitudes and the use of objective threshold determination techniques." @default.
• W2080541206 created "2016-06-24" @default.
• W2080541206 creator A5059266079 @default.
• W2080541206 creator A5088509529 @default.
• W2080541206 date "2008-11-01" @default.
• W2080541206 modified "2023-10-03" @default.
• W2080541206 title "Objective threshold estimation and measurement of the residual background noise in auditory evoked potentials of goldfish" @default.
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• W2080541206 doi "https://doi.org/10.1121/1.2982366" @default.
• W2080541206 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2677356" @default.
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