Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080550980> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2080550980 endingPage "926" @default.
- W2080550980 startingPage "919" @default.
- W2080550980 abstract "The interaction of normal and acute-phase high-density lipoproteins of the subclass 3 (N-HDL3 and AP-HDL3) with human neutrophils and the accompanying degradation of HDL3 apolipoproteins have been studied in vitro. The chemical composition of normal and acute-phase HDL3 was similar except that serum amyloid A protein (apo-SAA) was a major apolipoprotein in AP-HDL3 (approx. 30% of total apolipoproteins). 125I-labelled AP-HDL3 was degraded 5-10 times faster than 125I-labelled N-HDL3 during incubation with neutrophils or neutrophil-conditioned medium. Apo-SAA, like apolipoprotein A-II (apo-A-II), was more susceptible than apolipoprotein A-I (apo-A-I) to the action of proteases released from the cells. The amounts of cell-associated AP-HDL3 apolipoproteins at saturation were up to 2.8 times greater than N-HDL3 apolipoproteins; while apo-A-I was the major cell-associated apolipoprotein when N-HDL3 was bound, apo-SAA constituted 80% of the apolipoproteins bound in the case of AP-HDL3. The associated intact apo-SAA was mostly surface-bound as it was accessible to the action of exogenous trypsin. alpha 1-Antitrypsin-resistant (alpha 1-AT-resistant) cellular degradation of AP-HDL3 apolipoproteins also occurred; experiments in which pulse-chase labelling was performed or lysosomotropic agents were used indicated that insignificant intracellular degradation occurred which points to the involvement of cell-surface proteases in this degradation." @default.
- W2080550980 created "2016-06-24" @default.
- W2080550980 creator A5002466774 @default.
- W2080550980 creator A5021927797 @default.
- W2080550980 creator A5038379283 @default.
- W2080550980 creator A5058833764 @default.
- W2080550980 creator A5087999352 @default.
- W2080550980 creator A5090860934 @default.
- W2080550980 date "1987-12-15" @default.
- W2080550980 modified "2023-10-14" @default.
- W2080550980 title "Neutrophil association and degradation of normal and acute-phase high-density lipoprotein 3" @default.
- W2080550980 cites W102074104 @default.
- W2080550980 cites W1580333051 @default.
- W2080550980 cites W1586837086 @default.
- W2080550980 cites W1597030361 @default.
- W2080550980 cites W1641919774 @default.
- W2080550980 cites W1775749144 @default.
- W2080550980 cites W1878775584 @default.
- W2080550980 cites W1880502860 @default.
- W2080550980 cites W1979783822 @default.
- W2080550980 cites W2000523745 @default.
- W2080550980 cites W2004626037 @default.
- W2080550980 cites W2009898758 @default.
- W2080550980 cites W2017977654 @default.
- W2080550980 cites W2018289835 @default.
- W2080550980 cites W2032731208 @default.
- W2080550980 cites W2069860285 @default.
- W2080550980 cites W2097780936 @default.
- W2080550980 cites W2100837269 @default.
- W2080550980 cites W2130888600 @default.
- W2080550980 cites W2147558974 @default.
- W2080550980 cites W2161491104 @default.
- W2080550980 cites W2397183436 @default.
- W2080550980 cites W2437596932 @default.
- W2080550980 cites W295727357 @default.
- W2080550980 cites W87082738 @default.
- W2080550980 cites W277259137 @default.
- W2080550980 doi "https://doi.org/10.1042/bj2480919" @default.
- W2080550980 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1148637" @default.
- W2080550980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2449174" @default.
- W2080550980 hasPublicationYear "1987" @default.
- W2080550980 type Work @default.
- W2080550980 sameAs 2080550980 @default.
- W2080550980 citedByCount "38" @default.
- W2080550980 countsByYear W20805509802012 @default.
- W2080550980 countsByYear W20805509802015 @default.
- W2080550980 countsByYear W20805509802016 @default.
- W2080550980 countsByYear W20805509802022 @default.
- W2080550980 crossrefType "journal-article" @default.
- W2080550980 hasAuthorship W2080550980A5002466774 @default.
- W2080550980 hasAuthorship W2080550980A5021927797 @default.
- W2080550980 hasAuthorship W2080550980A5038379283 @default.
- W2080550980 hasAuthorship W2080550980A5058833764 @default.
- W2080550980 hasAuthorship W2080550980A5087999352 @default.
- W2080550980 hasAuthorship W2080550980A5090860934 @default.
- W2080550980 hasBestOaLocation W20805509802 @default.
- W2080550980 hasConcept C153911025 @default.
- W2080550980 hasConcept C181199279 @default.
- W2080550980 hasConcept C182220744 @default.
- W2080550980 hasConcept C185592680 @default.
- W2080550980 hasConcept C2778163477 @default.
- W2080550980 hasConcept C2780072125 @default.
- W2080550980 hasConcept C2780340462 @default.
- W2080550980 hasConcept C55493867 @default.
- W2080550980 hasConcept C62746215 @default.
- W2080550980 hasConcept C86803240 @default.
- W2080550980 hasConceptScore W2080550980C153911025 @default.
- W2080550980 hasConceptScore W2080550980C181199279 @default.
- W2080550980 hasConceptScore W2080550980C182220744 @default.
- W2080550980 hasConceptScore W2080550980C185592680 @default.
- W2080550980 hasConceptScore W2080550980C2778163477 @default.
- W2080550980 hasConceptScore W2080550980C2780072125 @default.
- W2080550980 hasConceptScore W2080550980C2780340462 @default.
- W2080550980 hasConceptScore W2080550980C55493867 @default.
- W2080550980 hasConceptScore W2080550980C62746215 @default.
- W2080550980 hasConceptScore W2080550980C86803240 @default.
- W2080550980 hasIssue "3" @default.
- W2080550980 hasLocation W20805509801 @default.
- W2080550980 hasLocation W20805509802 @default.
- W2080550980 hasLocation W20805509803 @default.
- W2080550980 hasLocation W20805509804 @default.
- W2080550980 hasOpenAccess W2080550980 @default.
- W2080550980 hasPrimaryLocation W20805509801 @default.
- W2080550980 hasRelatedWork W1541759791 @default.
- W2080550980 hasRelatedWork W1556580394 @default.
- W2080550980 hasRelatedWork W1862775393 @default.
- W2080550980 hasRelatedWork W1975878528 @default.
- W2080550980 hasRelatedWork W2003408138 @default.
- W2080550980 hasRelatedWork W2051916785 @default.
- W2080550980 hasRelatedWork W2089547944 @default.
- W2080550980 hasRelatedWork W2182434476 @default.
- W2080550980 hasRelatedWork W3024628464 @default.
- W2080550980 hasRelatedWork W4317623235 @default.
- W2080550980 hasVolume "248" @default.
- W2080550980 isParatext "false" @default.
- W2080550980 isRetracted "false" @default.
- W2080550980 magId "2080550980" @default.
- W2080550980 workType "article" @default.