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- W2080551476 abstract "888 The effect of carbohydrate supplementation on muscle glycogen storage and GLUT4 protein concentration was investigated 16 h after glycogen depleting exercise in Sprague-Dawley rats. Exercise significantly reduced fast red muscle glycogen by 50%. During the 16 h recovery, muscle glycogen retumed to control levels (25.0±1.4 μmol/g) in exercise-fasted rats (24.2±0.3 μmol/g), but muscle glycogen increased 77% above control (44.4±2.1 μmol/g) when carbohydrate supplementation was provided immediately post exercise. Exercise-fasting resulted in a 43% increase in GLUT4 protein concentration and an 80% increase in GLUT4 mRNA. Conversely, exercise-carbohydrate supplementation elevated fast red muscle GLUT4 protein concentration by 88% above control while GLUT4 mRNA was increased by only 40%. Neither a 16 h fast nor carbohydrate supplementation had an effect on fast red muscle GLUT4 protein concentration or GLUT4 mRNA in sedentary rats, although carbohydrate supplementation increased muscle glycogen concentration by 40% (35.0±0.9 μmol/g). Fast white muscle followed a pattern similar to fast red muscle. The results suggest that carbohydrate supplementation accelerates the exercise-induced increase in GLUT4 protein by translational and/or post translational mechanisms, and that post-exercise glycogen supercompensation may be partially due to an elevated GLUT4 protein expression. Supported by the American Diabetes Association" @default.
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- W2080551476 date "1999-05-01" @default.
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- W2080551476 title "CARBOHYDRATE SUPPLEMENTATION ACCELERATES THE EXERCISE-INDUCED INCREASE IN MUSCLE GLUT4 PROTEIN AND GLYCOGEN CONCENTRATIONS" @default.
- W2080551476 doi "https://doi.org/10.1097/00005768-199905001-00886" @default.
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