Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080593255> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2080593255 endingPage "309" @default.
- W2080593255 startingPage "305" @default.
- W2080593255 abstract "Background: Previous research has reported improved pain after adding methadone to another opioid, but did not quantify this benefit using a validated outcome measure. Objective: To assess quantitatively the effectiveness of adding methadone to another opioid for moderate to severe cancer-related pain. Design: All outpatients attending the Oncology Palliative Care Clinic from September 2010–September 2011, who had received methadone, were identified from pharmacy records. Inclusion criteria included: histological diagnosis of malignancy, age >18 years, taking regular opioids and Edmonton Symptom Assessment System (ESAS) pain score ≥4. Measurement: The primary outcome measure was a decrease in pain score of ≥2 points from methadone initiation to one-month follow-up (or closest available ESAS). Results: Twenty patients were available for analysis, 16 of whom had neuropathic pain (80%). Eight patients (40%) had a decrease in pain score of ≥2 points at 1 month and a further 7 (35%) had a decrease of ≥2 points at the closest available time point. The mean pain score decreased from 7.7 +/− 1.8 to 5.2 +/− 2.4 from time of initiation to time of evaluation. The mean daily routine morphine equivalent, (excluding methadone), was 338 +/− 217.8 mg/day at initiation and 332 +/− 191 mg/day at evaluation; for methadone, mean doses at initiation and evaluation were 4.4 +/− 1.4 mg/day and 15.5 +/− 5.9 mg/day, respectively. Methadone was well tolerated in 17 patients (85%). Conclusions: The addition of methadone was associated with improved pain control for patients with moderate to severe pain on another opioid and appears to offer a safe, well-tolerated and practical alternative in this situation." @default.
- W2080593255 created "2016-06-24" @default.
- W2080593255 creator A5002514103 @default.
- W2080593255 creator A5017794183 @default.
- W2080593255 creator A5055774990 @default.
- W2080593255 creator A5075287766 @default.
- W2080593255 creator A5079164578 @default.
- W2080593255 date "2013-03-01" @default.
- W2080593255 modified "2023-09-27" @default.
- W2080593255 title "Addition of Methadone to Another Opioid in the Management of Moderate to Severe Cancer Pain: A Case Series" @default.
- W2080593255 cites W1965522233 @default.
- W2080593255 cites W1966497215 @default.
- W2080593255 cites W2013187174 @default.
- W2080593255 cites W2028351745 @default.
- W2080593255 cites W2040732127 @default.
- W2080593255 cites W2044459467 @default.
- W2080593255 cites W2045489192 @default.
- W2080593255 cites W2047297864 @default.
- W2080593255 cites W2059494370 @default.
- W2080593255 cites W2064160269 @default.
- W2080593255 cites W2072800295 @default.
- W2080593255 cites W2085772474 @default.
- W2080593255 cites W2092139176 @default.
- W2080593255 cites W2099079090 @default.
- W2080593255 cites W2110328570 @default.
- W2080593255 cites W2130655328 @default.
- W2080593255 cites W2139436147 @default.
- W2080593255 cites W67906064 @default.
- W2080593255 doi "https://doi.org/10.1089/jpm.2012.0335" @default.
- W2080593255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23391350" @default.
- W2080593255 hasPublicationYear "2013" @default.
- W2080593255 type Work @default.
- W2080593255 sameAs 2080593255 @default.
- W2080593255 citedByCount "23" @default.
- W2080593255 countsByYear W20805932552014 @default.
- W2080593255 countsByYear W20805932552016 @default.
- W2080593255 countsByYear W20805932552018 @default.
- W2080593255 countsByYear W20805932552019 @default.
- W2080593255 countsByYear W20805932552020 @default.
- W2080593255 countsByYear W20805932552021 @default.
- W2080593255 countsByYear W20805932552022 @default.
- W2080593255 countsByYear W20805932552023 @default.
- W2080593255 crossrefType "journal-article" @default.
- W2080593255 hasAuthorship W2080593255A5002514103 @default.
- W2080593255 hasAuthorship W2080593255A5017794183 @default.
- W2080593255 hasAuthorship W2080593255A5055774990 @default.
- W2080593255 hasAuthorship W2080593255A5075287766 @default.
- W2080593255 hasAuthorship W2080593255A5079164578 @default.
- W2080593255 hasConcept C104863432 @default.
- W2080593255 hasConcept C121608353 @default.
- W2080593255 hasConcept C126322002 @default.
- W2080593255 hasConcept C159110408 @default.
- W2080593255 hasConcept C170493617 @default.
- W2080593255 hasConcept C2777107010 @default.
- W2080593255 hasConcept C2777389121 @default.
- W2080593255 hasConcept C2778767360 @default.
- W2080593255 hasConcept C2778904085 @default.
- W2080593255 hasConcept C2781063702 @default.
- W2080593255 hasConcept C2909746581 @default.
- W2080593255 hasConcept C2994186709 @default.
- W2080593255 hasConcept C42219234 @default.
- W2080593255 hasConcept C512399662 @default.
- W2080593255 hasConcept C71924100 @default.
- W2080593255 hasConceptScore W2080593255C104863432 @default.
- W2080593255 hasConceptScore W2080593255C121608353 @default.
- W2080593255 hasConceptScore W2080593255C126322002 @default.
- W2080593255 hasConceptScore W2080593255C159110408 @default.
- W2080593255 hasConceptScore W2080593255C170493617 @default.
- W2080593255 hasConceptScore W2080593255C2777107010 @default.
- W2080593255 hasConceptScore W2080593255C2777389121 @default.
- W2080593255 hasConceptScore W2080593255C2778767360 @default.
- W2080593255 hasConceptScore W2080593255C2778904085 @default.
- W2080593255 hasConceptScore W2080593255C2781063702 @default.
- W2080593255 hasConceptScore W2080593255C2909746581 @default.
- W2080593255 hasConceptScore W2080593255C2994186709 @default.
- W2080593255 hasConceptScore W2080593255C42219234 @default.
- W2080593255 hasConceptScore W2080593255C512399662 @default.
- W2080593255 hasConceptScore W2080593255C71924100 @default.
- W2080593255 hasIssue "3" @default.
- W2080593255 hasLocation W20805932551 @default.
- W2080593255 hasLocation W20805932552 @default.
- W2080593255 hasOpenAccess W2080593255 @default.
- W2080593255 hasPrimaryLocation W20805932551 @default.
- W2080593255 hasRelatedWork W1837738291 @default.
- W2080593255 hasRelatedWork W2000801346 @default.
- W2080593255 hasRelatedWork W2028419780 @default.
- W2080593255 hasRelatedWork W2037560904 @default.
- W2080593255 hasRelatedWork W2075267799 @default.
- W2080593255 hasRelatedWork W2587011781 @default.
- W2080593255 hasRelatedWork W3181681555 @default.
- W2080593255 hasRelatedWork W4230100933 @default.
- W2080593255 hasRelatedWork W4295106475 @default.
- W2080593255 hasRelatedWork W1033819662 @default.
- W2080593255 hasVolume "16" @default.
- W2080593255 isParatext "false" @default.
- W2080593255 isRetracted "false" @default.
- W2080593255 magId "2080593255" @default.
- W2080593255 workType "article" @default.