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- W2080598068 abstract "In the present experiment male Sprague-Dawley rats at three different ages (young, middle-aged, and old) were tested in a series of olfactory-mediated behavioral tests. The amount of ano-genital investigation directed to receptive females by old rats was significantly reduced compared to that of young and middle-aged animals. In contrast, general body investigation of receptive females was similar among the three age groups. The amount of anogenital investigation directed to nonreceptive females or immature male rats indicated significant differences only between young and old rats, with values from middle-aged rats being intermediate and not significantly different from either of the two extreme groups. General body investigation of nonreceptive females and immature males did not differ among the three age groups. Old rats showed the best performance in a location of buried food test with latencies to locate food approximately one-half that obtained from young and middle-aged rats. Measures of general locomotor activity indicated significantly greater values from young compared to middle-aged and old rats, with the latter two showing very similar levels. These results demonstrate clear discriminatory differences in olfactory-mediated behavioral performance of the male rat as a function of the specific test and age of the animal. Overall, the results suggest that olfactory-mediated behaviors related to reproduction appear more sensitive to age-related declines, while behavior related to food procurement is more minimally affected." @default.
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- W2080598068 title "Age-dependent changes in olfactory-mediated behavioral investigations in the male rat" @default.
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