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- W2080603442 abstract "Neomycin was used to assess the involvement of Ins (1,4,5)P 3 in the Ca 2+ release from the endoplasmic reticulum induced by the bile acid taurolithocholate. In saponin‐permeabilized rat hepatocytes, neomycin via its ability to bind Ins (1,4,5)P 3 abolished the release of Ca 2+ induced by added Ins (1,4,5)P 3 . In contrast, it did not alter the Ca 2+ release initiated by the bile acid. In intact cells, neomycin had no effect on the [Ca 2+ ] i rises promoted by taurolithocholate and vasopressin. It is suggested that the effect of taurolithocholate in liver is not mediated by Ins (1,4,5)P 3 but results from a primary action on endoplasmic reticulum." @default.
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- W2080603442 date "1988-01-25" @default.
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- W2080603442 title "Effect of the bile acid taurolithocholate on cell calcium in saponin-treated rat hepatocytes" @default.
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- W2080603442 doi "https://doi.org/10.1016/0014-5793(88)80889-5" @default.
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