Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080649613> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2080649613 endingPage "434" @default.
- W2080649613 startingPage "427" @default.
- W2080649613 abstract "1. Drug-induced neurological disease is a relatively common problem. For example, the Boston Collaborative Drug Surveillance Program reported that in 11,526 hospitalized patients, 14.2% of adverse drug reactions (ADRs) were neurological. 2. Drugs can induce various syndromes such as: disturbances of consciousness, psychiatric disorders, headache, cranial nerve disorders, movement disorders, psychosis, peripheral neuropathy, myopathy and autonomic dysfunction. 3. The vast majority of ADRs are dose-related (e.g. CNS depression by sedative-hypnotics). In these cases the frequency and severity of the ADRs is proportional to the administered dose, therefore, they can be prevented and/or treated by adjusting the dosage to patient's needs. Dose-unrelated ADRs (e.g. malignant hyperthermia by various anaesthetic agents) are uncommon and the development of the reaction is mainly dependent on increased patient's susceptibility. Accordingly, the ADR can only be prevented by not readministering the drug. 4. Most of the evidence associating specific drugs with neurological adverse events comes from single case reports in which no systematic assessment of causality has been made. Recently, valid and reliable definitions of ADRs have been reported (e.g. Kramer et al, 1979; Naranjo et al, 1981). The systematic application of these methods greatly reduce the ambiguity for analyzing alleged cases of ADRs. These methods can be easily applied by practising physicians in the assessment and reporting of suspected drug-induced neurological diseases." @default.
- W2080649613 created "2016-06-24" @default.
- W2080649613 creator A5013791504 @default.
- W2080649613 creator A5020943975 @default.
- W2080649613 creator A5072848571 @default.
- W2080649613 date "1981-01-01" @default.
- W2080649613 modified "2023-09-27" @default.
- W2080649613 title "Clinical detection and assessment of drug induced neurotoxicity" @default.
- W2080649613 cites W1990388631 @default.
- W2080649613 cites W1990687682 @default.
- W2080649613 cites W2014977713 @default.
- W2080649613 cites W2022737882 @default.
- W2080649613 cites W2029692218 @default.
- W2080649613 cites W2032416563 @default.
- W2080649613 cites W2039854206 @default.
- W2080649613 cites W2067978628 @default.
- W2080649613 cites W2074119085 @default.
- W2080649613 cites W2087992824 @default.
- W2080649613 cites W4247139476 @default.
- W2080649613 cites W4293202440 @default.
- W2080649613 cites W4323283751 @default.
- W2080649613 doi "https://doi.org/10.1016/0364-7722(81)90024-2" @default.
- W2080649613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6280224" @default.
- W2080649613 hasPublicationYear "1981" @default.
- W2080649613 type Work @default.
- W2080649613 sameAs 2080649613 @default.
- W2080649613 citedByCount "6" @default.
- W2080649613 countsByYear W20806496132013 @default.
- W2080649613 countsByYear W20806496132014 @default.
- W2080649613 countsByYear W20806496132017 @default.
- W2080649613 crossrefType "journal-article" @default.
- W2080649613 hasAuthorship W2080649613A5013791504 @default.
- W2080649613 hasAuthorship W2080649613A5020943975 @default.
- W2080649613 hasAuthorship W2080649613A5072848571 @default.
- W2080649613 hasConcept C118552586 @default.
- W2080649613 hasConcept C126322002 @default.
- W2080649613 hasConcept C139719470 @default.
- W2080649613 hasConcept C162324750 @default.
- W2080649613 hasConcept C177713679 @default.
- W2080649613 hasConcept C187212893 @default.
- W2080649613 hasConcept C197934379 @default.
- W2080649613 hasConcept C2776867660 @default.
- W2080649613 hasConcept C2777300911 @default.
- W2080649613 hasConcept C2779727114 @default.
- W2080649613 hasConcept C2780035454 @default.
- W2080649613 hasConcept C2780542314 @default.
- W2080649613 hasConcept C2993432071 @default.
- W2080649613 hasConcept C42219234 @default.
- W2080649613 hasConcept C71924100 @default.
- W2080649613 hasConceptScore W2080649613C118552586 @default.
- W2080649613 hasConceptScore W2080649613C126322002 @default.
- W2080649613 hasConceptScore W2080649613C139719470 @default.
- W2080649613 hasConceptScore W2080649613C162324750 @default.
- W2080649613 hasConceptScore W2080649613C177713679 @default.
- W2080649613 hasConceptScore W2080649613C187212893 @default.
- W2080649613 hasConceptScore W2080649613C197934379 @default.
- W2080649613 hasConceptScore W2080649613C2776867660 @default.
- W2080649613 hasConceptScore W2080649613C2777300911 @default.
- W2080649613 hasConceptScore W2080649613C2779727114 @default.
- W2080649613 hasConceptScore W2080649613C2780035454 @default.
- W2080649613 hasConceptScore W2080649613C2780542314 @default.
- W2080649613 hasConceptScore W2080649613C2993432071 @default.
- W2080649613 hasConceptScore W2080649613C42219234 @default.
- W2080649613 hasConceptScore W2080649613C71924100 @default.
- W2080649613 hasIssue "5-6" @default.
- W2080649613 hasLocation W20806496131 @default.
- W2080649613 hasLocation W20806496132 @default.
- W2080649613 hasOpenAccess W2080649613 @default.
- W2080649613 hasPrimaryLocation W20806496131 @default.
- W2080649613 hasRelatedWork W1589946262 @default.
- W2080649613 hasRelatedWork W2018736125 @default.
- W2080649613 hasRelatedWork W2142225926 @default.
- W2080649613 hasRelatedWork W2368117378 @default.
- W2080649613 hasRelatedWork W2373673832 @default.
- W2080649613 hasRelatedWork W2375393165 @default.
- W2080649613 hasRelatedWork W2376738370 @default.
- W2080649613 hasRelatedWork W2377211821 @default.
- W2080649613 hasRelatedWork W2736011018 @default.
- W2080649613 hasRelatedWork W3031362645 @default.
- W2080649613 hasVolume "5" @default.
- W2080649613 isParatext "false" @default.
- W2080649613 isRetracted "false" @default.
- W2080649613 magId "2080649613" @default.
- W2080649613 workType "article" @default.