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- W2080658906 abstract "The 5-HT1A and 5-HT2A receptor affinity of model 1-(2-pyrimidinyl)-piperazine derivatives 15-21 and 23-32 has been determined. 2-(N-Methylpiperazino)-4,6-di(2-thienyl)pyrimidine 26 is a new, highly active and selective 5-HT2A receptor ligand. The topography of a molecule and the stereoelectronic effects of the thiophene rings are the major factors responsible for the high affinity and selectivity of 26 towards 5-HT2A sites." @default.
- W2080658906 created "2016-06-24" @default.
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- W2080658906 date "1995-04-18" @default.
- W2080658906 modified "2023-09-24" @default.
- W2080658906 title "ChemInform Abstract: Structure-Activity Relationship Studies of CNS Agents. Part 14. Structural Requirements for the 5-HT1A and 5-HT2A Receptor Selectivity of Simple 1-(2-Pyrimidinyl)piperazine Derivatives." @default.
- W2080658906 doi "https://doi.org/10.1002/chin.199516180" @default.
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