FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080661034> ?p ?o ?g. }

• W2080661034 endingPage "568" @default.
• W2080661034 startingPage "562" @default.
• W2080661034 abstract "OBJECTIVE: Multiple clinical trials demonstrate the value of administering antibiotics for recurrent tonsillitis. However, there is no consensus as to the role of antibiotics in the management of adenotonsillar hypertrophy and obstructive sleep apnea (OSA). It has been suggested that antibiotics may reduce adenotonsillar size, improve obstructive symptoms, and obviate the need for surgery. The goal of this pilot study was to evaluate the efficacy of a broad-spectrum antibiotic in the management of adenotonsillar hypertrophy and OSA. METHODS: Twenty-two children ages 2 through 12, with evidence of OSA, were enrolled in this double-blinded, prospective clinical trial. Children were randomly assigned into 1 of 2 groups. Group I received azithromycin for a 30-day period (12 mg/kg on days 1-5; the regimen was repeated on days 11-15 and days 21-25). Group II received a placebo administered in the same regimen for a 30-day period. Overnight polysomnography was performed before and within 2 weeks after drug administration. RESULTS: Polysomnographic indices of OSA severity appear to indicate an improvement in the antibiotic as compared to the placebo group, but a comparison of mean ± standard error for each parameter failed to demonstrate statistical significance using the paired t test. Only 1 of 11 (9%) children had normalization of their polysomnographic parameters. CONCLUSIONS: These results suggest that a course of a broad-spectrum antibiotic may be effective in temporarily improving OSA due to adenotonsillar hypertrophy, but does not appear to obviate the need for surgery." @default.
• W2080661034 created "2016-06-24" @default.
• W2080661034 creator A5001277337 @default.
• W2080661034 creator A5022484936 @default.
• W2080661034 creator A5024640970 @default.
• W2080661034 creator A5064784673 @default.
• W2080661034 date "2005-10-01" @default.
• W2080661034 modified "2023-10-18" @default.
• W2080661034 title "Antimicrobial Therapy for Children with Adenotonsillar Hypertrophy and Obstructive Sleep Apnea: A Prospective Randomized Trial Comparing Azithromycin vs Placebo" @default.
• W2080661034 cites W1495536584 @default.
• W2080661034 cites W194140197 @default.
• W2080661034 cites W1975255985 @default.
• W2080661034 cites W2005615218 @default.
• W2080661034 cites W2006410524 @default.
• W2080661034 cites W2008562258 @default.
• W2080661034 cites W2009171069 @default.
• W2080661034 cites W2013068228 @default.
• W2080661034 cites W2013703185 @default.
• W2080661034 cites W2020155836 @default.
• W2080661034 cites W2029061336 @default.
• W2080661034 cites W2035073627 @default.
• W2080661034 cites W2053348226 @default.
• W2080661034 cites W2054151807 @default.
• W2080661034 cites W2057225629 @default.
• W2080661034 cites W2074072665 @default.
• W2080661034 cites W2074596047 @default.
• W2080661034 cites W2099957092 @default.
• W2080661034 cites W2128111243 @default.
• W2080661034 cites W2149512898 @default.
• W2080661034 cites W2322645385 @default.
• W2080661034 cites W2342929865 @default.
• W2080661034 doi "https://doi.org/10.1016/j.otohns.2005.05.012" @default.
• W2080661034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16213930" @default.
• W2080661034 hasPublicationYear "2005" @default.
• W2080661034 type Work @default.
• W2080661034 sameAs 2080661034 @default.
• W2080661034 citedByCount "28" @default.
• W2080661034 countsByYear W20806610342012 @default.
• W2080661034 countsByYear W20806610342013 @default.
• W2080661034 countsByYear W20806610342014 @default.
• W2080661034 countsByYear W20806610342015 @default.
• W2080661034 countsByYear W20806610342016 @default.
• W2080661034 countsByYear W20806610342018 @default.
• W2080661034 countsByYear W20806610342019 @default.
• W2080661034 countsByYear W20806610342020 @default.
• W2080661034 countsByYear W20806610342021 @default.
• W2080661034 countsByYear W20806610342022 @default.
• W2080661034 countsByYear W20806610342023 @default.
• W2080661034 crossrefType "journal-article" @default.
• W2080661034 hasAuthorship W2080661034A5001277337 @default.
• W2080661034 hasAuthorship W2080661034A5022484936 @default.
• W2080661034 hasAuthorship W2080661034A5024640970 @default.
• W2080661034 hasAuthorship W2080661034A5064784673 @default.
• W2080661034 hasConcept C126322002 @default.
• W2080661034 hasConcept C142724271 @default.
• W2080661034 hasConcept C168563851 @default.
• W2080661034 hasConcept C188816634 @default.
• W2080661034 hasConcept C204787440 @default.
• W2080661034 hasConcept C27081682 @default.
• W2080661034 hasConcept C2776006263 @default.
• W2080661034 hasConcept C2778205975 @default.
• W2080661034 hasConcept C2778907293 @default.
• W2080661034 hasConcept C2781326671 @default.
• W2080661034 hasConcept C2781413609 @default.
• W2080661034 hasConcept C501593827 @default.
• W2080661034 hasConcept C535046627 @default.
• W2080661034 hasConcept C65409693 @default.
• W2080661034 hasConcept C71924100 @default.
• W2080661034 hasConcept C86803240 @default.
• W2080661034 hasConcept C89423630 @default.
• W2080661034 hasConceptScore W2080661034C126322002 @default.
• W2080661034 hasConceptScore W2080661034C142724271 @default.
• W2080661034 hasConceptScore W2080661034C168563851 @default.
• W2080661034 hasConceptScore W2080661034C188816634 @default.
• W2080661034 hasConceptScore W2080661034C204787440 @default.
• W2080661034 hasConceptScore W2080661034C27081682 @default.
• W2080661034 hasConceptScore W2080661034C2776006263 @default.
• W2080661034 hasConceptScore W2080661034C2778205975 @default.
• W2080661034 hasConceptScore W2080661034C2778907293 @default.
• W2080661034 hasConceptScore W2080661034C2781326671 @default.
• W2080661034 hasConceptScore W2080661034C2781413609 @default.
• W2080661034 hasConceptScore W2080661034C501593827 @default.
• W2080661034 hasConceptScore W2080661034C535046627 @default.
• W2080661034 hasConceptScore W2080661034C65409693 @default.
• W2080661034 hasConceptScore W2080661034C71924100 @default.
• W2080661034 hasConceptScore W2080661034C86803240 @default.
• W2080661034 hasConceptScore W2080661034C89423630 @default.
• W2080661034 hasIssue "4" @default.
• W2080661034 hasLocation W20806610341 @default.
• W2080661034 hasLocation W20806610342 @default.
• W2080661034 hasOpenAccess W2080661034 @default.
• W2080661034 hasPrimaryLocation W20806610341 @default.
• W2080661034 hasRelatedWork W2165614801 @default.
• W2080661034 hasRelatedWork W2186303850 @default.
• W2080661034 hasRelatedWork W2223590006 @default.
• W2080661034 hasRelatedWork W2383496458 @default.
• W2080661034 hasRelatedWork W2385244159 @default.
• W2080661034 hasRelatedWork W2385652705 @default.

• next