Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080671323> ?p ?o ?g. }
- W2080671323 endingPage "350" @default.
- W2080671323 startingPage "341" @default.
- W2080671323 abstract "Years of clinical research to treat disorders such as peptic ulcers and obstructive lung disease with the first generation of modestly selective M1 antagonists (e.g. pirenzepine, telenzepine) have been disappointing. For some indications (chronic obstructive pulmonary disease), nonselective antagonists (ipratropium bromide) have exhibited better clinical efficacy. The advent of a new generation of centrally active and highly selective M1 antagonists, such as PD150714, spirotramine FC1594, (-)-S-ET126 and R-4-(pyrrolidino)-1-(4-fluorophenylcarbamoyloxy)-1-phenyl-2-butyne (4-F-PhPyMcN), offers new opportunities for using selective muscarinic agents as therapeutic agents or research tools." @default.
- W2080671323 created "2016-06-24" @default.
- W2080671323 creator A5056531508 @default.
- W2080671323 creator A5059800254 @default.
- W2080671323 creator A5061148360 @default.
- W2080671323 date "1997-08-01" @default.
- W2080671323 modified "2023-10-18" @default.
- W2080671323 title "Selective muscarinic M1 antagonists: drug design and discovery" @default.
- W2080671323 cites W1491110744 @default.
- W2080671323 cites W167486056 @default.
- W2080671323 cites W1866773095 @default.
- W2080671323 cites W1874938414 @default.
- W2080671323 cites W1964664572 @default.
- W2080671323 cites W1966069671 @default.
- W2080671323 cites W1972574226 @default.
- W2080671323 cites W1974018894 @default.
- W2080671323 cites W1977306763 @default.
- W2080671323 cites W1981199626 @default.
- W2080671323 cites W1983286360 @default.
- W2080671323 cites W1984761742 @default.
- W2080671323 cites W1985593573 @default.
- W2080671323 cites W1987672231 @default.
- W2080671323 cites W1988428440 @default.
- W2080671323 cites W1990105869 @default.
- W2080671323 cites W1994067502 @default.
- W2080671323 cites W1994998873 @default.
- W2080671323 cites W1997709939 @default.
- W2080671323 cites W2000087538 @default.
- W2080671323 cites W2002664465 @default.
- W2080671323 cites W2007480720 @default.
- W2080671323 cites W2020736372 @default.
- W2080671323 cites W2022307318 @default.
- W2080671323 cites W2022664472 @default.
- W2080671323 cites W2028238425 @default.
- W2080671323 cites W2037422738 @default.
- W2080671323 cites W2038151405 @default.
- W2080671323 cites W2039142992 @default.
- W2080671323 cites W2039654930 @default.
- W2080671323 cites W2039918394 @default.
- W2080671323 cites W2044685366 @default.
- W2080671323 cites W2049552190 @default.
- W2080671323 cites W2049748148 @default.
- W2080671323 cites W2052072990 @default.
- W2080671323 cites W2055599589 @default.
- W2080671323 cites W2058510604 @default.
- W2080671323 cites W2059857806 @default.
- W2080671323 cites W2060588252 @default.
- W2080671323 cites W2061695514 @default.
- W2080671323 cites W2062470717 @default.
- W2080671323 cites W2065433771 @default.
- W2080671323 cites W2067661404 @default.
- W2080671323 cites W2067931832 @default.
- W2080671323 cites W2071111322 @default.
- W2080671323 cites W2072348105 @default.
- W2080671323 cites W2083407012 @default.
- W2080671323 cites W2085702311 @default.
- W2080671323 cites W2092326818 @default.
- W2080671323 cites W2092775058 @default.
- W2080671323 cites W2093360381 @default.
- W2080671323 cites W2113630547 @default.
- W2080671323 cites W2130885282 @default.
- W2080671323 cites W2162727642 @default.
- W2080671323 cites W2315025335 @default.
- W2080671323 cites W4210957931 @default.
- W2080671323 cites W4235351690 @default.
- W2080671323 cites W4243694051 @default.
- W2080671323 cites W4252932587 @default.
- W2080671323 doi "https://doi.org/10.1016/s1359-6446(97)01076-3" @default.
- W2080671323 hasPublicationYear "1997" @default.
- W2080671323 type Work @default.
- W2080671323 sameAs 2080671323 @default.
- W2080671323 citedByCount "10" @default.
- W2080671323 countsByYear W20806713232012 @default.
- W2080671323 countsByYear W20806713232013 @default.
- W2080671323 crossrefType "journal-article" @default.
- W2080671323 hasAuthorship W2080671323A5056531508 @default.
- W2080671323 hasAuthorship W2080671323A5059800254 @default.
- W2080671323 hasAuthorship W2080671323A5061148360 @default.
- W2080671323 hasConcept C126322002 @default.
- W2080671323 hasConcept C170493617 @default.
- W2080671323 hasConcept C2776042228 @default.
- W2080671323 hasConcept C2778616617 @default.
- W2080671323 hasConcept C2778689640 @default.
- W2080671323 hasConcept C2780035454 @default.
- W2080671323 hasConcept C2780532441 @default.
- W2080671323 hasConcept C2781018748 @default.
- W2080671323 hasConcept C33789571 @default.
- W2080671323 hasConcept C60644358 @default.
- W2080671323 hasConcept C71924100 @default.
- W2080671323 hasConcept C74187038 @default.
- W2080671323 hasConcept C86803240 @default.
- W2080671323 hasConcept C98274493 @default.
- W2080671323 hasConceptScore W2080671323C126322002 @default.
- W2080671323 hasConceptScore W2080671323C170493617 @default.
- W2080671323 hasConceptScore W2080671323C2776042228 @default.
- W2080671323 hasConceptScore W2080671323C2778616617 @default.
- W2080671323 hasConceptScore W2080671323C2778689640 @default.
- W2080671323 hasConceptScore W2080671323C2780035454 @default.