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• W2080683498 abstract "Recent drug discovery programs targeting urokinase plasminogen activator (uPA) have resulted in nonpeptidic inhibitors consisting of amidine or guanidine functional groups attached to aromatic or heteroaromatic scaffolds. There is a general problem of poor oral bioavailability of these charged inhibitors. In this paper, we report the synthesis and evaluation of a series of naphthamide and naphthalene sulfonamides as uPA inhibitors containing non-basic groups as substitute for amidine or guanidine groups." @default.
• W2080683498 created "2016-06-24" @default.
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• W2080683498 date "2012-02-01" @default.
• W2080683498 modified "2023-09-26" @default.
• W2080683498 title "Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)" @default.
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• W2080683498 doi "https://doi.org/10.1016/j.bmc.2011.12.040" @default.
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