Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080684015> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2080684015 abstract "To assess whether heterogeneity of epidermal growth factor receptor (EGFR) immunoreactivity in renal cell carcinoma (RCC) is related to non-standardised criteria for staining evaluation.EGFR expression was investigated in 132 primary and 55 metastatic conventional RCCs using a tissue microarray technique.Overall, membranous and/or cytoplasmic EGFR immunostaining was present in 123 of 132 (93%) primary and 49 of 53 (92%) metastatic RCCs, with extensive immunoreactivity (> 50% of tumour cells) in 110 of 132 (83%) primary tumours and 39 of 53 (73%) metastases. Cytoplasmic staining was associated with high tumour stage and high tumour grade. In addition, strong membranous staining (score 3+) prevailed in high grade RCCs. Cytoplasmic immunostaining was associated with an unfavourable prognosis, whereas overall (cytoplasmic and membranous) immunoreactivity and intensity of membranous staining were not.Different methods of immunohistochemical evaluation led to different results, strengthening the need for standardisation, especially against a background of rapidly evolving EGFR targeted cancer treatment strategies." @default.
- W2080684015 created "2016-06-24" @default.
- W2080684015 creator A5007093204 @default.
- W2080684015 creator A5033387762 @default.
- W2080684015 creator A5036101921 @default.
- W2080684015 creator A5058168074 @default.
- W2080684015 creator A5086021741 @default.
- W2080684015 date "2004-07-01" @default.
- W2080684015 modified "2023-09-24" @default.
- W2080684015 title "Are heterogenous results of EGFR immunoreactivity in renal cell carcinoma related to non-standardised criteria for staining evaluation?" @default.
- W2080684015 cites W2025255125 @default.
- W2080684015 cites W2026221868 @default.
- W2080684015 cites W2039633811 @default.
- W2080684015 cites W2041881143 @default.
- W2080684015 cites W2051962096 @default.
- W2080684015 cites W2087810003 @default.
- W2080684015 cites W2137895670 @default.
- W2080684015 cites W2395026578 @default.
- W2080684015 cites W2408232533 @default.
- W2080684015 doi "https://doi.org/10.1136/jcp.2003.015743" @default.
- W2080684015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1770368" @default.
- W2080684015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15220376" @default.
- W2080684015 hasPublicationYear "2004" @default.
- W2080684015 type Work @default.
- W2080684015 sameAs 2080684015 @default.
- W2080684015 citedByCount "47" @default.
- W2080684015 countsByYear W20806840152012 @default.
- W2080684015 countsByYear W20806840152013 @default.
- W2080684015 countsByYear W20806840152014 @default.
- W2080684015 countsByYear W20806840152015 @default.
- W2080684015 countsByYear W20806840152019 @default.
- W2080684015 countsByYear W20806840152021 @default.
- W2080684015 crossrefType "journal-article" @default.
- W2080684015 hasAuthorship W2080684015A5007093204 @default.
- W2080684015 hasAuthorship W2080684015A5033387762 @default.
- W2080684015 hasAuthorship W2080684015A5036101921 @default.
- W2080684015 hasAuthorship W2080684015A5058168074 @default.
- W2080684015 hasAuthorship W2080684015A5086021741 @default.
- W2080684015 hasBestOaLocation W20806840151 @default.
- W2080684015 hasConcept C121608353 @default.
- W2080684015 hasConcept C126322002 @default.
- W2080684015 hasConcept C142724271 @default.
- W2080684015 hasConcept C190062978 @default.
- W2080684015 hasConcept C193270364 @default.
- W2080684015 hasConcept C204232928 @default.
- W2080684015 hasConcept C2777472916 @default.
- W2080684015 hasConcept C2777546739 @default.
- W2080684015 hasConcept C2778560582 @default.
- W2080684015 hasConcept C2779438470 @default.
- W2080684015 hasConcept C4224716 @default.
- W2080684015 hasConcept C55493867 @default.
- W2080684015 hasConcept C71924100 @default.
- W2080684015 hasConcept C74864618 @default.
- W2080684015 hasConcept C86803240 @default.
- W2080684015 hasConceptScore W2080684015C121608353 @default.
- W2080684015 hasConceptScore W2080684015C126322002 @default.
- W2080684015 hasConceptScore W2080684015C142724271 @default.
- W2080684015 hasConceptScore W2080684015C190062978 @default.
- W2080684015 hasConceptScore W2080684015C193270364 @default.
- W2080684015 hasConceptScore W2080684015C204232928 @default.
- W2080684015 hasConceptScore W2080684015C2777472916 @default.
- W2080684015 hasConceptScore W2080684015C2777546739 @default.
- W2080684015 hasConceptScore W2080684015C2778560582 @default.
- W2080684015 hasConceptScore W2080684015C2779438470 @default.
- W2080684015 hasConceptScore W2080684015C4224716 @default.
- W2080684015 hasConceptScore W2080684015C55493867 @default.
- W2080684015 hasConceptScore W2080684015C71924100 @default.
- W2080684015 hasConceptScore W2080684015C74864618 @default.
- W2080684015 hasConceptScore W2080684015C86803240 @default.
- W2080684015 hasLocation W20806840151 @default.
- W2080684015 hasLocation W20806840152 @default.
- W2080684015 hasLocation W20806840153 @default.
- W2080684015 hasLocation W20806840154 @default.
- W2080684015 hasOpenAccess W2080684015 @default.
- W2080684015 hasPrimaryLocation W20806840151 @default.
- W2080684015 hasRelatedWork W1565767041 @default.
- W2080684015 hasRelatedWork W2055113126 @default.
- W2080684015 hasRelatedWork W2080684015 @default.
- W2080684015 hasRelatedWork W2084136175 @default.
- W2080684015 hasRelatedWork W2109129376 @default.
- W2080684015 hasRelatedWork W2168881876 @default.
- W2080684015 hasRelatedWork W2242689536 @default.
- W2080684015 hasRelatedWork W2318988265 @default.
- W2080684015 hasRelatedWork W2577499001 @default.
- W2080684015 hasRelatedWork W2742519752 @default.
- W2080684015 isParatext "false" @default.
- W2080684015 isRetracted "false" @default.
- W2080684015 magId "2080684015" @default.
- W2080684015 workType "article" @default.