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- W2080693810 abstract "A pharmacokinetic analysis of the distribution of a drug into a perfused organ or hypothetical compartment of the body yields mathematical expressions which may be useful for ascertaining if the distribution of a drug is rate limited by the flow of the perfusate, by the diffusion of the drug from the perfusate into the organ, or if it is a function of both of these processes. These expressions have been used to analyze the distribution of a drug from a perfusing fluid into the isolated perfused rat liver, and of several drugs from a hypothetical central compartment to a hypothetical peripheral compartment in man." @default.
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- W2080693810 date "1968-11-01" @default.
- W2080693810 modified "2023-10-18" @default.
- W2080693810 title "Effect of Flow Rate on the Distribution Kinetics of a Drug From Perfusate to a Perfused Organ" @default.
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- W2080693810 doi "https://doi.org/10.1002/jps.2600571140" @default.
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