Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080710138> ?p ?o ?g. }
- W2080710138 endingPage "1001" @default.
- W2080710138 startingPage "994" @default.
- W2080710138 abstract "The effect of exercise at different intensities as well as the effect of intensive supervised pulmonary rehabilitation on oxidative stress were studied for chronic obstructive pulmonary disease (COPD). Eleven patients with COPD and 11 healthy age-matched control subjects performed a maximal and submaximal exercise cycle ergometry test at 60% of peak workload. Patients with COPD performed these tests before and after 8 wk of pulmonary rehabilitation. Measurements were done before, immediately after, and 4 h after both exercise tests. At rest, increased oxidative stress was observed in patients compared with control subjects, as measured by urinary malondialdehyde (MDA; p < 0.05) and hydrogen peroxide (H2O2) in breath condensate (p < 0.05). In healthy control subjects, a significant increase in urinary MDA was observed 4 h after both exercise tests (p = 0.05), whereas H2O2 significantly increased immediately after maximal exercise (p < 0.05). In patients with COPD, before rehabilitation, reactive oxygen species–induced DNA damage in peripheral blood mononuclear cells, urinary MDA, and plasma uric acid were significantly increased after both exercise tests (p < 0.05), whereas no significant increase was observed in plasma MDA. In contrast, exhaled H2O2 was only significantly increased after maximal exercise (p < 0.02). Although after rehabilitation peak workload was increased by 24%, a similar oxidative stress response was found. Remarkably, a decrease in reactive oxygen species–induced DNA damage was detected after exercise at submaximal intensity despite increased exercise duration of 73%. In summary, patients with COPD had increased pulmonary and systemic oxidative stress both at rest and induced by exercise. In addition, pulmonary rehabilitation increased exercise capacity and was associated with reduced exercise-induced oxidative stress." @default.
- W2080710138 created "2016-06-24" @default.
- W2080710138 creator A5013717261 @default.
- W2080710138 creator A5055885747 @default.
- W2080710138 creator A5061953007 @default.
- W2080710138 creator A5062244556 @default.
- W2080710138 creator A5062699123 @default.
- W2080710138 creator A5084729994 @default.
- W2080710138 date "2005-10-15" @default.
- W2080710138 modified "2023-10-16" @default.
- W2080710138 title "Rehabilitation Decreases Exercise-induced Oxidative Stress in Chronic Obstructive Pulmonary Disease" @default.
- W2080710138 cites W1964715280 @default.
- W2080710138 cites W1968529406 @default.
- W2080710138 cites W1968846145 @default.
- W2080710138 cites W1969665190 @default.
- W2080710138 cites W1988481400 @default.
- W2080710138 cites W1990482858 @default.
- W2080710138 cites W1993253783 @default.
- W2080710138 cites W2004683841 @default.
- W2080710138 cites W2006322923 @default.
- W2080710138 cites W2010468968 @default.
- W2080710138 cites W2016581979 @default.
- W2080710138 cites W2020424703 @default.
- W2080710138 cites W2031916922 @default.
- W2080710138 cites W2033882509 @default.
- W2080710138 cites W2036412531 @default.
- W2080710138 cites W2038519294 @default.
- W2080710138 cites W2041369332 @default.
- W2080710138 cites W2045616259 @default.
- W2080710138 cites W2061026040 @default.
- W2080710138 cites W2078047263 @default.
- W2080710138 cites W2079843433 @default.
- W2080710138 cites W2086410495 @default.
- W2080710138 cites W2090864985 @default.
- W2080710138 cites W2091335681 @default.
- W2080710138 cites W2091806638 @default.
- W2080710138 cites W2092629964 @default.
- W2080710138 cites W2106694672 @default.
- W2080710138 cites W2109977819 @default.
- W2080710138 cites W2111736273 @default.
- W2080710138 cites W2115734416 @default.
- W2080710138 cites W2121954647 @default.
- W2080710138 cites W2122653386 @default.
- W2080710138 cites W2123084333 @default.
- W2080710138 cites W2126902508 @default.
- W2080710138 cites W2132826785 @default.
- W2080710138 cites W2134675753 @default.
- W2080710138 cites W2143343444 @default.
- W2080710138 cites W2156107878 @default.
- W2080710138 cites W2162376947 @default.
- W2080710138 cites W2163699185 @default.
- W2080710138 cites W2164453868 @default.
- W2080710138 cites W2166804883 @default.
- W2080710138 cites W2170168774 @default.
- W2080710138 cites W2324148764 @default.
- W2080710138 cites W2412808135 @default.
- W2080710138 cites W2994597783 @default.
- W2080710138 doi "https://doi.org/10.1164/rccm.200411-1580oc" @default.
- W2080710138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16040783" @default.
- W2080710138 hasPublicationYear "2005" @default.
- W2080710138 type Work @default.
- W2080710138 sameAs 2080710138 @default.
- W2080710138 citedByCount "171" @default.
- W2080710138 countsByYear W20807101382012 @default.
- W2080710138 countsByYear W20807101382013 @default.
- W2080710138 countsByYear W20807101382014 @default.
- W2080710138 countsByYear W20807101382015 @default.
- W2080710138 countsByYear W20807101382016 @default.
- W2080710138 countsByYear W20807101382017 @default.
- W2080710138 countsByYear W20807101382018 @default.
- W2080710138 countsByYear W20807101382019 @default.
- W2080710138 countsByYear W20807101382020 @default.
- W2080710138 countsByYear W20807101382021 @default.
- W2080710138 countsByYear W20807101382022 @default.
- W2080710138 countsByYear W20807101382023 @default.
- W2080710138 crossrefType "journal-article" @default.
- W2080710138 hasAuthorship W2080710138A5013717261 @default.
- W2080710138 hasAuthorship W2080710138A5055885747 @default.
- W2080710138 hasAuthorship W2080710138A5061953007 @default.
- W2080710138 hasAuthorship W2080710138A5062244556 @default.
- W2080710138 hasAuthorship W2080710138A5062699123 @default.
- W2080710138 hasAuthorship W2080710138A5084729994 @default.
- W2080710138 hasConcept C126322002 @default.
- W2080710138 hasConcept C164705383 @default.
- W2080710138 hasConcept C181588539 @default.
- W2080710138 hasConcept C1862650 @default.
- W2080710138 hasConcept C196310339 @default.
- W2080710138 hasConcept C2776151105 @default.
- W2080710138 hasConcept C2776780178 @default.
- W2080710138 hasConcept C2777953023 @default.
- W2080710138 hasConcept C2778401633 @default.
- W2080710138 hasConcept C2780779891 @default.
- W2080710138 hasConcept C71924100 @default.
- W2080710138 hasConcept C84393581 @default.
- W2080710138 hasConceptScore W2080710138C126322002 @default.
- W2080710138 hasConceptScore W2080710138C164705383 @default.
- W2080710138 hasConceptScore W2080710138C181588539 @default.
- W2080710138 hasConceptScore W2080710138C1862650 @default.