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- W2080711921 abstract "Abstract A new method for the assay of fluspirilene (R 6218) in dosage forms using HPLC has been developed. The instrument used had a low volume positive displacement pump, a universal injector, a single wavelength (254 nm) detector, and a data module. The column was stainless steel 30 cm × 4 mm i.d. packed with microparticulate silica. The mobile phase consisted of equal volumes of chloroform and methanol at a flow rate of 1 ml per min. A linear relationship (r = 0.999) was obtained between peak area and concentration of fluspirilene in the range 10–200 μg per ml; no internal standard was used. Fluspirilene was extracted from injectable aqueous suspensions by membrane filtration, drying and dissolution in chloroform-methanol (1:1). Results of assaying fluspirilene in two commercial injectable suspensions by this method were 99.73 and 99.78% of labelled amount." @default.
- W2080711921 created "2016-06-24" @default.
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- W2080711921 date "1982-01-01" @default.
- W2080711921 modified "2023-09-26" @default.
- W2080711921 title "A New High Performance Liquid Chromatographic Assay for Fluspirilene in Dosage Forms" @default.
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- W2080711921 doi "https://doi.org/10.1080/01483918208067628" @default.
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