FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080753419> ?p ?o ?g. }

• W2080753419 endingPage "1427" @default.
• W2080753419 startingPage "1408" @default.
• W2080753419 abstract "Summary Aromatic organic compounds that are present in the environment can have toxic effects or provide carbon sources for bacteria. We report here the global response of Bacillus subtilis 168 to phenol and catechol using proteome and transcriptome analyses. Phenol induced the HrcA, σ B and CtsR heat‐shock regulons as well as the Spx disulfide stress regulon. Catechol caused the activation of the HrcA and CtsR heat‐shock regulons and a thiol‐specific oxidative stress response involving the Spx, PerR and FurR regulons but no induction of the σ B regulon. The most surprising result was that several catabolite‐controlled genes are derepressed by catechol, even if glucose is taken up under these conditions. This derepression of the carbon catabolite control was dependent on the glucose concentration in the medium, as glucose excess increased the derepression of the CcpA‐dependent lichenin utilization licBCAH operon and the ribose metabolism rbsRKDACB operon by catechol. Growth and viability experiments with catechol as sole carbon source suggested that B. subtilis is not able to utilize catechol as a carbon‐energy source. In addition, the microarray results revealed the very strong induction of the yfiDE operon by catechol of which the yfiE gene shares similarities to glyoxalases/bleomycin resistance proteins/extradiol dioxygenases. Using recombinant His 6 ‐YfiE Bs we demonstrate that YfiE shows catechol‐2,3‐dioxygenase activity in the presence of catechol as the metabolite 2‐hydroxymuconic semialdehyde was measured. Furthermore, both genes of the yfiDE operon are essential for the growth and viability of B. subtilis in the presence of catechol. Thus, our studies revealed that the catechol‐2,3‐dioxygenase YfiE is the key enzyme of a meta cleavage pathway in B. subtilis involved in the catabolism of catechol." @default.
• W2080753419 created "2016-06-24" @default.
• W2080753419 creator A5013558846 @default.
• W2080753419 creator A5020611058 @default.
• W2080753419 creator A5062121412 @default.
• W2080753419 creator A5069535171 @default.
• W2080753419 creator A5075564856 @default.
• W2080753419 creator A5081649546 @default.
• W2080753419 creator A5082748007 @default.
• W2080753419 date "2006-04-26" @default.
• W2080753419 modified "2023-10-16" @default.
• W2080753419 title "Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis" @default.
• W2080753419 cites W1524702486 @default.
• W2080753419 cites W1571497143 @default.
• W2080753419 cites W1598801131 @default.
• W2080753419 cites W1633808858 @default.
• W2080753419 cites W1678194650 @default.
• W2080753419 cites W1780083071 @default.
• W2080753419 cites W1867594499 @default.
• W2080753419 cites W1873199501 @default.
• W2080753419 cites W1909878702 @default.
• W2080753419 cites W1918985758 @default.
• W2080753419 cites W1929452298 @default.
• W2080753419 cites W1952598685 @default.
• W2080753419 cites W1972711141 @default.
• W2080753419 cites W1979666686 @default.
• W2080753419 cites W1980832220 @default.
• W2080753419 cites W1981384832 @default.
• W2080753419 cites W1985279295 @default.
• W2080753419 cites W1985653246 @default.
• W2080753419 cites W1992233625 @default.
• W2080753419 cites W1995413408 @default.
• W2080753419 cites W2000981059 @default.
• W2080753419 cites W2013943606 @default.
• W2080753419 cites W2015969616 @default.
• W2080753419 cites W2037024099 @default.
• W2080753419 cites W2037767853 @default.
• W2080753419 cites W2048367222 @default.
• W2080753419 cites W2050257011 @default.
• W2080753419 cites W2052244339 @default.
• W2080753419 cites W2056099004 @default.
• W2080753419 cites W2071699980 @default.
• W2080753419 cites W2078239820 @default.
• W2080753419 cites W2091215023 @default.
• W2080753419 cites W2094011156 @default.
• W2080753419 cites W2096859475 @default.
• W2080753419 cites W2099083388 @default.
• W2080753419 cites W2102977495 @default.
• W2080753419 cites W2104268624 @default.
• W2080753419 cites W2107311753 @default.
• W2080753419 cites W2109535113 @default.
• W2080753419 cites W2118204420 @default.
• W2080753419 cites W2123856846 @default.
• W2080753419 cites W2130412668 @default.
• W2080753419 cites W2134331533 @default.
• W2080753419 cites W2136150036 @default.
• W2080753419 cites W2136317897 @default.
• W2080753419 cites W2136499912 @default.
• W2080753419 cites W2138081694 @default.
• W2080753419 cites W2138307025 @default.
• W2080753419 cites W2141409273 @default.
• W2080753419 cites W2146595893 @default.
• W2080753419 cites W2146968515 @default.
• W2080753419 cites W2160463209 @default.
• W2080753419 cites W2161630640 @default.
• W2080753419 cites W2165301921 @default.
• W2080753419 cites W2168225803 @default.
• W2080753419 cites W4293247451 @default.
• W2080753419 doi "https://doi.org/10.1111/j.1462-2920.2006.01034.x" @default.
• W2080753419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16872404" @default.
• W2080753419 hasPublicationYear "2006" @default.
• W2080753419 type Work @default.
• W2080753419 sameAs 2080753419 @default.
• W2080753419 citedByCount "88" @default.
• W2080753419 countsByYear W20807534192012 @default.
• W2080753419 countsByYear W20807534192013 @default.
• W2080753419 countsByYear W20807534192014 @default.
• W2080753419 countsByYear W20807534192015 @default.
• W2080753419 countsByYear W20807534192016 @default.
• W2080753419 countsByYear W20807534192017 @default.
• W2080753419 countsByYear W20807534192018 @default.
• W2080753419 countsByYear W20807534192019 @default.
• W2080753419 countsByYear W20807534192020 @default.
• W2080753419 countsByYear W20807534192021 @default.
• W2080753419 countsByYear W20807534192022 @default.
• W2080753419 countsByYear W20807534192023 @default.
• W2080753419 crossrefType "journal-article" @default.
• W2080753419 hasAuthorship W2080753419A5013558846 @default.
• W2080753419 hasAuthorship W2080753419A5020611058 @default.
• W2080753419 hasAuthorship W2080753419A5062121412 @default.
• W2080753419 hasAuthorship W2080753419A5069535171 @default.
• W2080753419 hasAuthorship W2080753419A5075564856 @default.
• W2080753419 hasAuthorship W2080753419A5081649546 @default.
• W2080753419 hasAuthorship W2080753419A5082748007 @default.
• W2080753419 hasConcept C101762097 @default.
• W2080753419 hasConcept C104317684 @default.
• W2080753419 hasConcept C137984847 @default.
• W2080753419 hasConcept C143065580 @default.

• next