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- W2080766013 abstract "Haptoglobin (Hpt) is a plasma protein with hemoglobin-binding capacity. It is a well-known marker of hemolysis. Hpt is also an acute-phase protein that functions as a bacteriostatic agent, an inhibitor of prostaglandin synthesis and angiogenesis. However, the best-known biological function of Hpt is capture of hemoglobin (Hb). The identification of functional differences in haptoglobin molecules resulting from relatively common polymorphisms has further elucidated the importance of haptoglobin in iron homeostasis and in disease processes influenced by iron metabolism. In this review the effect of Hpt polymorphism on these different disease entities will be discussed." @default.
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- W2080766013 date "2004-07-01" @default.
- W2080766013 modified "2023-10-16" @default.
- W2080766013 title "Haptoglobin polymorphisms and iron homeostasis in health and in disease" @default.
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- W2080766013 doi "https://doi.org/10.1016/j.cccn.2004.03.016" @default.
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