FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080779692> ?p ?o ?g. }

• W2080779692 endingPage "9873" @default.
• W2080779692 startingPage "9872" @default.
• W2080779692 abstract "Here we report that the phenanthridine derivative covalently linked to a fluorescein moiety (FLEth) can act as a fluorescence based probe for duplex short interfering RNA (siRNA) and that this probe can also be used to report on protein−RNA interactions. A fluorescence resonance energy transfer (FRET) signal that is observed at 600 nm occurs when FLEth is complexed with siRNA. At least 2 molecules of FLEth can bind to 21 nt duplex siRNA, and the dissociation constants for these interactions are reported. We find that FLEth can also report on the interaction of siRNAs with the Carnation Italian ringspot viral suppressor of RNA silencing p19. FLEth does not bind to the siRNA−p19 complex nor can p19 bind to the siRNA−FLEth complex; rather FLEth can report on the fraction of siRNA that is unbound. FLEth can also bind siRNA in delivery systems such as liposomes. Once the siRNA reaches the interior of Huh 7.5 cells, FLEth dissociates from the siRNA and is found in the nucleoli suggesting that FLEth cannot bind to siRNAs that are associated with the RNA silencing machinery." @default.
• W2080779692 created "2016-06-24" @default.
• W2080779692 creator A5017585282 @default.
• W2080779692 creator A5024297093 @default.
• W2080779692 creator A5025305214 @default.
• W2080779692 creator A5028002699 @default.
• W2080779692 creator A5030436387 @default.
• W2080779692 creator A5056030836 @default.
• W2080779692 creator A5079114989 @default.
• W2080779692 creator A5089509154 @default.
• W2080779692 date "2009-07-07" @default.
• W2080779692 modified "2023-10-17" @default.
• W2080779692 title "FLEth RNA Intercalating Probe Is a Convenient Reporter for Small Interfering RNAs" @default.
• W2080779692 cites W1611419331 @default.
• W2080779692 cites W1647075334 @default.
• W2080779692 cites W1916491745 @default.
• W2080779692 cites W1969865366 @default.
• W2080779692 cites W1974670254 @default.
• W2080779692 cites W1982131024 @default.
• W2080779692 cites W1992336935 @default.
• W2080779692 cites W2054901989 @default.
• W2080779692 cites W2060085008 @default.
• W2080779692 cites W2060570235 @default.
• W2080779692 cites W2073658360 @default.
• W2080779692 cites W2091446481 @default.
• W2080779692 cites W2104761776 @default.
• W2080779692 cites W2111831519 @default.
• W2080779692 cites W2116603538 @default.
• W2080779692 cites W2117991391 @default.
• W2080779692 cites W2134176045 @default.
• W2080779692 cites W2142450960 @default.
• W2080779692 cites W2153038484 @default.
• W2080779692 cites W2159746639 @default.
• W2080779692 cites W4211039187 @default.
• W2080779692 doi "https://doi.org/10.1021/ja902636m" @default.
• W2080779692 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2731296" @default.
• W2080779692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19583254" @default.
• W2080779692 hasPublicationYear "2009" @default.
• W2080779692 type Work @default.
• W2080779692 sameAs 2080779692 @default.
• W2080779692 citedByCount "15" @default.
• W2080779692 countsByYear W20807796922013 @default.
• W2080779692 countsByYear W20807796922014 @default.
• W2080779692 countsByYear W20807796922015 @default.
• W2080779692 countsByYear W20807796922016 @default.
• W2080779692 countsByYear W20807796922018 @default.
• W2080779692 countsByYear W20807796922019 @default.
• W2080779692 countsByYear W20807796922020 @default.
• W2080779692 countsByYear W20807796922021 @default.
• W2080779692 countsByYear W20807796922023 @default.
• W2080779692 crossrefType "journal-article" @default.
• W2080779692 hasAuthorship W2080779692A5017585282 @default.
• W2080779692 hasAuthorship W2080779692A5024297093 @default.
• W2080779692 hasAuthorship W2080779692A5025305214 @default.
• W2080779692 hasAuthorship W2080779692A5028002699 @default.
• W2080779692 hasAuthorship W2080779692A5030436387 @default.
• W2080779692 hasAuthorship W2080779692A5056030836 @default.
• W2080779692 hasAuthorship W2080779692A5079114989 @default.
• W2080779692 hasAuthorship W2080779692A5089509154 @default.
• W2080779692 hasBestOaLocation W20807796922 @default.
• W2080779692 hasConcept C104317684 @default.
• W2080779692 hasConcept C119056186 @default.
• W2080779692 hasConcept C121332964 @default.
• W2080779692 hasConcept C12554922 @default.
• W2080779692 hasConcept C153911025 @default.
• W2080779692 hasConcept C166703698 @default.
• W2080779692 hasConcept C185592680 @default.
• W2080779692 hasConcept C2191507 @default.
• W2080779692 hasConcept C22615655 @default.
• W2080779692 hasConcept C55493867 @default.
• W2080779692 hasConcept C60723119 @default.
• W2080779692 hasConcept C62520636 @default.
• W2080779692 hasConcept C67705224 @default.
• W2080779692 hasConcept C86803240 @default.
• W2080779692 hasConcept C91881484 @default.
• W2080779692 hasConcept C95444343 @default.
• W2080779692 hasConcept C96305047 @default.
• W2080779692 hasConceptScore W2080779692C104317684 @default.
• W2080779692 hasConceptScore W2080779692C119056186 @default.
• W2080779692 hasConceptScore W2080779692C121332964 @default.
• W2080779692 hasConceptScore W2080779692C12554922 @default.
• W2080779692 hasConceptScore W2080779692C153911025 @default.
• W2080779692 hasConceptScore W2080779692C166703698 @default.
• W2080779692 hasConceptScore W2080779692C185592680 @default.
• W2080779692 hasConceptScore W2080779692C2191507 @default.
• W2080779692 hasConceptScore W2080779692C22615655 @default.
• W2080779692 hasConceptScore W2080779692C55493867 @default.
• W2080779692 hasConceptScore W2080779692C60723119 @default.
• W2080779692 hasConceptScore W2080779692C62520636 @default.
• W2080779692 hasConceptScore W2080779692C67705224 @default.
• W2080779692 hasConceptScore W2080779692C86803240 @default.
• W2080779692 hasConceptScore W2080779692C91881484 @default.
• W2080779692 hasConceptScore W2080779692C95444343 @default.
• W2080779692 hasConceptScore W2080779692C96305047 @default.
• W2080779692 hasIssue "29" @default.
• W2080779692 hasLocation W20807796921 @default.
• W2080779692 hasLocation W20807796922 @default.
• W2080779692 hasLocation W20807796923 @default.

• next