Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080782826> ?p ?o ?g. }
- W2080782826 endingPage "1155" @default.
- W2080782826 startingPage "1144" @default.
- W2080782826 abstract "Pharmacological sodium nitrate supplementation has been reported to reduce the O 2 cost of submaximal exercise in humans. In this study, we hypothesized that dietary supplementation with inorganic nitrate in the form of beetroot juice (BR) would reduce the O 2 cost of submaximal exercise and enhance the tolerance to high-intensity exercise. In a double-blind, placebo (PL)-controlled, crossover study, eight men (aged 19–38 yr) consumed 500 ml/day of either BR (containing 11.2 ± 0.6 mM of nitrate) or blackcurrant cordial (as a PL, with negligible nitrate content) for 6 consecutive days and completed a series of “step” moderate-intensity and severe-intensity exercise tests on the last 3 days. On days 4–6, plasma nitrite concentration was significantly greater following dietary nitrate supplementation compared with PL (BR: 273 ± 44 vs. PL: 140 ± 50 nM; P < 0.05), and systolic blood pressure was significantly reduced (BR: 124 ± 2 vs. PL: 132 ± 5 mmHg; P < 0.01). During moderate exercise, nitrate supplementation reduced muscle fractional O 2 extraction (as estimated using near-infrared spectroscopy). The gain of the increase in pulmonary O 2 uptake following the onset of moderate exercise was reduced by 19% in the BR condition (BR: 8.6 ± 0.7 vs. PL: 10.8 ± 1.6 ml·min −1 ·W −1 ; P < 0.05). During severe exercise, the O 2 uptake slow component was reduced (BR: 0.57 ± 0.20 vs. PL: 0.74 ± 0.24 l/min; P < 0.05), and the time-to-exhaustion was extended (BR: 675 ± 203 vs. PL: 583 ± 145 s; P < 0.05). The reduced O 2 cost of exercise following increased dietary nitrate intake has important implications for our understanding of the factors that regulate mitochondrial respiration and muscle contractile energetics in humans." @default.
- W2080782826 created "2016-06-24" @default.
- W2080782826 creator A5001353396 @default.
- W2080782826 creator A5027978067 @default.
- W2080782826 creator A5042238470 @default.
- W2080782826 creator A5042670819 @default.
- W2080782826 creator A5062262348 @default.
- W2080782826 creator A5066987914 @default.
- W2080782826 creator A5072915358 @default.
- W2080782826 creator A5085933197 @default.
- W2080782826 creator A5089965367 @default.
- W2080782826 date "2009-10-01" @default.
- W2080782826 modified "2023-10-03" @default.
- W2080782826 title "Dietary nitrate supplementation reduces the O<sub>2</sub>cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans" @default.
- W2080782826 cites W1481335435 @default.
- W2080782826 cites W1495363069 @default.
- W2080782826 cites W157277420 @default.
- W2080782826 cites W1574625282 @default.
- W2080782826 cites W1638150453 @default.
- W2080782826 cites W1957992664 @default.
- W2080782826 cites W1958523161 @default.
- W2080782826 cites W1964847650 @default.
- W2080782826 cites W1966441631 @default.
- W2080782826 cites W1971128407 @default.
- W2080782826 cites W1974061713 @default.
- W2080782826 cites W1979459504 @default.
- W2080782826 cites W1985227130 @default.
- W2080782826 cites W1991308916 @default.
- W2080782826 cites W1994515174 @default.
- W2080782826 cites W1994875454 @default.
- W2080782826 cites W1995322594 @default.
- W2080782826 cites W2005831500 @default.
- W2080782826 cites W2007744953 @default.
- W2080782826 cites W2008579796 @default.
- W2080782826 cites W2009013636 @default.
- W2080782826 cites W2016139728 @default.
- W2080782826 cites W2021901278 @default.
- W2080782826 cites W2021952329 @default.
- W2080782826 cites W2022276077 @default.
- W2080782826 cites W2022295123 @default.
- W2080782826 cites W2028641769 @default.
- W2080782826 cites W2032684043 @default.
- W2080782826 cites W2036352285 @default.
- W2080782826 cites W2037111212 @default.
- W2080782826 cites W2039387002 @default.
- W2080782826 cites W2041124801 @default.
- W2080782826 cites W2044756386 @default.
- W2080782826 cites W2044926225 @default.
- W2080782826 cites W2047545717 @default.
- W2080782826 cites W2050008654 @default.
- W2080782826 cites W2058062846 @default.
- W2080782826 cites W2059418292 @default.
- W2080782826 cites W2065464327 @default.
- W2080782826 cites W2068395093 @default.
- W2080782826 cites W2071755029 @default.
- W2080782826 cites W2077988634 @default.
- W2080782826 cites W2078178926 @default.
- W2080782826 cites W2086725891 @default.
- W2080782826 cites W2087869104 @default.
- W2080782826 cites W2088810650 @default.
- W2080782826 cites W2109560819 @default.
- W2080782826 cites W2116642215 @default.
- W2080782826 cites W2117389490 @default.
- W2080782826 cites W2120200123 @default.
- W2080782826 cites W2122246435 @default.
- W2080782826 cites W2126330593 @default.
- W2080782826 cites W2130121105 @default.
- W2080782826 cites W2136280068 @default.
- W2080782826 cites W2142137775 @default.
- W2080782826 cites W2145139856 @default.
- W2080782826 cites W2152287206 @default.
- W2080782826 cites W2158923004 @default.
- W2080782826 cites W2159358865 @default.
- W2080782826 cites W2160427475 @default.
- W2080782826 cites W2160615772 @default.
- W2080782826 cites W2161221966 @default.
- W2080782826 cites W2176052317 @default.
- W2080782826 cites W2178177034 @default.
- W2080782826 cites W2180753399 @default.
- W2080782826 cites W2337938000 @default.
- W2080782826 doi "https://doi.org/10.1152/japplphysiol.00722.2009" @default.
- W2080782826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19661447" @default.
- W2080782826 hasPublicationYear "2009" @default.
- W2080782826 type Work @default.
- W2080782826 sameAs 2080782826 @default.
- W2080782826 citedByCount "627" @default.
- W2080782826 countsByYear W20807828262012 @default.
- W2080782826 countsByYear W20807828262013 @default.
- W2080782826 countsByYear W20807828262014 @default.
- W2080782826 countsByYear W20807828262015 @default.
- W2080782826 countsByYear W20807828262016 @default.
- W2080782826 countsByYear W20807828262017 @default.
- W2080782826 countsByYear W20807828262018 @default.
- W2080782826 countsByYear W20807828262019 @default.
- W2080782826 countsByYear W20807828262020 @default.
- W2080782826 countsByYear W20807828262021 @default.
- W2080782826 countsByYear W20807828262022 @default.
- W2080782826 countsByYear W20807828262023 @default.