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- W2080805498 abstract "Quorum sensing is a type of bacterial communication mediated by chemical signaling molecules called autoinducers (AIs). The production of AI-2 and AI-3 is dependent on the luxS gene in Escherichia coli O157:H7. A luxS mutation caused a minimal decrease (about 2-fold) in Shiga toxin (Stx) production in in vitro cultures using Luria-Bertani broth. The effect of a luxS mutation on the virulence of E. coli O157:H7 was examined by using germfree mice. There were no differences between the luxS mutant and the wild-type in the bacterial counts in feces shedding, Stx production, or the survival of the mice. The treatment of ciprofloxacin decreased the bacteria in feces but increased the Stx production. However, even treatment with ciprofloxacin did not make any difference between the luxS mutant and the wild-type in animal experiments." @default.
- W2080805498 created "2016-06-24" @default.
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- W2080805498 date "2007-04-01" @default.
- W2080805498 modified "2023-10-01" @default.
- W2080805498 title "Production of Shiga Toxin by aluxSMutant ofEscherichia coliO157:H7In VivoandIn Vitro" @default.
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- W2080805498 doi "https://doi.org/10.1111/j.1348-0421.2007.tb03926.x" @default.
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