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• W2080821235 abstract "The utility of nurse-administered propofol sedation (NAPS) compared with midazolam and meperidine (M/M) for EUS is not known.To compare recovery times, costs, safety, health personnel, and patient satisfaction of NAPS and M/M for EUS.Prospective, randomized, single-blinded trial.Tertiary-referral hospital in Indianapolis, Indiana.Outpatients referred for EUS.Sedation with M/M or NAPS. The patient and recovery nurse were blinded; however, the sedating nurse, endoscopist, and recording research nurse were unblinded to the sedatives used. A capnography, in addition to standard monitoring, was used. A questionnaire and visual analog scale assessed patient, endoscopist, and sedating nurse satisfaction.Recovery times, costs, safety, health personnel, and patient satisfaction in both groups.Eighty consecutive patients were randomized to NAPS (n = 40) or M/M (n = 40). More patients in the propofol group were current tobacco users; patient demographics, procedures performed, mean procedure length, and the overall frequency of adverse events were otherwise similar. Compared with M/M, NAPS was associated with a faster induction of sedation (2.3 vs 5.7 minutes, respectively; P = .001) and full recovery time (29 vs 49 minutes, respectively; P = .001), higher postprocedure patient satisfaction, and quicker anticipated return to baseline function. At discharge, total costs (recovery plus medications) were similar between the propofol ($406) and M/M groups ($399; P = .79).Low-risk patient population.Compared with M/M, NAPS for an EUS offered a faster sedation induction and full recovery time, higher postprocedure patient satisfaction, and a quicker anticipated return to baseline function. Total costs were similar between the groups." @default.
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• W2080821235 date "2008-09-01" @default.
• W2080821235 modified "2023-10-15" @default.
• W2080821235 title "Nurse-administered propofol sedation compared with midazolam and meperidine for EUS: a prospective, randomized trial" @default.
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• W2080821235 doi "https://doi.org/10.1016/j.gie.2008.02.092" @default.
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