FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080856488> ?p ?o ?g. }

• W2080856488 endingPage "11" @default.
• W2080856488 startingPage "6" @default.
• W2080856488 abstract "Elevated levels of IL-1β have been found in synovial fluid from patients with temporomandibular disorders (TMD) and are thought to be involved in pain and progression of TMD. Synovial cells in the temporomandibular joint have important roles in progression of synovitis ; however, their biological roles are poorly understood. In this study, we examined the effect of IL-1β on gene expression in synovial fibroblast cultures from 5 different patients. Gene expression was monitored by Affymetrix GeneChip analysis and real-time PCR. Gro-α protein level was measured by ELISA. Among the genes with altered expression, GeneChip analysis detected increased Gro-α mRNA in fibroblasts from all 5 synovial specimens. This increased Gro-α gene expression was confirmed by real-time PCR. Gro-α protein was preferentially increased by IL-1β in synovial fibroblasts. Gro-α has chemotactic effects on lymphocytes and monocytes, and it also regulates endothelial cell proliferation and stimulates angiogenesis. When these established effects are taken together with the results presented herein, increased gene expression and protein production of Gro-α in synovial fibroblasts in response to IL-1β appears to play an important role in recruitment of inflammatory cells into the synovium and in progression of synovitis." @default.
• W2080856488 created "2016-06-24" @default.
• W2080856488 creator A5004726722 @default.
• W2080856488 creator A5006615953 @default.
• W2080856488 creator A5063068613 @default.
• W2080856488 creator A5083277157 @default.
• W2080856488 date "2006-01-01" @default.
• W2080856488 modified "2023-10-10" @default.
• W2080856488 title "Stimulation of Gro-.ALPHA. Gene Expression and Production by IL-I.BETA. in Synovial Fibroblasts from Human Temporomandibular Joints" @default.
• W2080856488 cites W1502713942 @default.
• W2080856488 cites W1571798928 @default.
• W2080856488 cites W1600880529 @default.
• W2080856488 cites W1723301197 @default.
• W2080856488 cites W1780460389 @default.
• W2080856488 cites W1973195685 @default.
• W2080856488 cites W1974996960 @default.
• W2080856488 cites W1975410914 @default.
• W2080856488 cites W1989058068 @default.
• W2080856488 cites W2017822480 @default.
• W2080856488 cites W2029532091 @default.
• W2080856488 cites W2037135840 @default.
• W2080856488 cites W2057674617 @default.
• W2080856488 cites W2058725566 @default.
• W2080856488 cites W2076182160 @default.
• W2080856488 cites W2078586454 @default.
• W2080856488 cites W2082968812 @default.
• W2080856488 cites W2093119949 @default.
• W2080856488 cites W2102167914 @default.
• W2080856488 cites W2103269080 @default.
• W2080856488 cites W2123797864 @default.
• W2080856488 cites W2134812217 @default.
• W2080856488 cites W2136869074 @default.
• W2080856488 cites W2164998957 @default.
• W2080856488 cites W2343428206 @default.
• W2080856488 doi "https://doi.org/10.5466/ijoms.5.6" @default.
• W2080856488 hasPublicationYear "2006" @default.
• W2080856488 type Work @default.
• W2080856488 sameAs 2080856488 @default.
• W2080856488 citedByCount "1" @default.
• W2080856488 countsByYear W20808564882014 @default.
• W2080856488 crossrefType "journal-article" @default.
• W2080856488 hasAuthorship W2080856488A5004726722 @default.
• W2080856488 hasAuthorship W2080856488A5006615953 @default.
• W2080856488 hasAuthorship W2080856488A5063068613 @default.
• W2080856488 hasAuthorship W2080856488A5083277157 @default.
• W2080856488 hasBestOaLocation W20808564881 @default.
• W2080856488 hasConcept C104317684 @default.
• W2080856488 hasConcept C142724271 @default.
• W2080856488 hasConcept C150194340 @default.
• W2080856488 hasConcept C153911025 @default.
• W2080856488 hasConcept C203014093 @default.
• W2080856488 hasConcept C2776914184 @default.
• W2080856488 hasConcept C2777077863 @default.
• W2080856488 hasConcept C2777652487 @default.
• W2080856488 hasConcept C2779244835 @default.
• W2080856488 hasConcept C2780381497 @default.
• W2080856488 hasConcept C2780394083 @default.
• W2080856488 hasConcept C502942594 @default.
• W2080856488 hasConcept C54355233 @default.
• W2080856488 hasConcept C55493867 @default.
• W2080856488 hasConcept C71924100 @default.
• W2080856488 hasConcept C81885089 @default.
• W2080856488 hasConcept C86803240 @default.
• W2080856488 hasConceptScore W2080856488C104317684 @default.
• W2080856488 hasConceptScore W2080856488C142724271 @default.
• W2080856488 hasConceptScore W2080856488C150194340 @default.
• W2080856488 hasConceptScore W2080856488C153911025 @default.
• W2080856488 hasConceptScore W2080856488C203014093 @default.
• W2080856488 hasConceptScore W2080856488C2776914184 @default.
• W2080856488 hasConceptScore W2080856488C2777077863 @default.
• W2080856488 hasConceptScore W2080856488C2777652487 @default.
• W2080856488 hasConceptScore W2080856488C2779244835 @default.
• W2080856488 hasConceptScore W2080856488C2780381497 @default.
• W2080856488 hasConceptScore W2080856488C2780394083 @default.
• W2080856488 hasConceptScore W2080856488C502942594 @default.
• W2080856488 hasConceptScore W2080856488C54355233 @default.
• W2080856488 hasConceptScore W2080856488C55493867 @default.
• W2080856488 hasConceptScore W2080856488C71924100 @default.
• W2080856488 hasConceptScore W2080856488C81885089 @default.
• W2080856488 hasConceptScore W2080856488C86803240 @default.
• W2080856488 hasIssue "1" @default.
• W2080856488 hasLocation W20808564881 @default.
• W2080856488 hasOpenAccess W2080856488 @default.
• W2080856488 hasPrimaryLocation W20808564881 @default.
• W2080856488 hasRelatedWork W2009966535 @default.
• W2080856488 hasRelatedWork W2044000768 @default.
• W2080856488 hasRelatedWork W2056172754 @default.
• W2080856488 hasRelatedWork W2065367715 @default.
• W2080856488 hasRelatedWork W2095011332 @default.
• W2080856488 hasRelatedWork W2130690212 @default.
• W2080856488 hasRelatedWork W2360416811 @default.
• W2080856488 hasRelatedWork W2373507912 @default.
• W2080856488 hasRelatedWork W2406549227 @default.
• W2080856488 hasRelatedWork W2409632590 @default.
• W2080856488 hasVolume "5" @default.
• W2080856488 isParatext "false" @default.
• W2080856488 isRetracted "false" @default.
• W2080856488 magId "2080856488" @default.

• next