FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080867526> ?p ?o ?g. }

• W2080867526 endingPage "9" @default.
• W2080867526 startingPage "1" @default.
• W2080867526 abstract "Present experiments examined whether previously observed hormone-dependent differences in norepinephrine-stimulated cAMP accumulation in hypothalamic and preoptic area slices are attributable to differences in noradrenergic receptor number or binding affinity. When compared to ovariectomized controls, hypothalamic and preoptic area membranes from estradiol-treated rats had significantly elevated numbers of [3H]prazosin (α1) binding sites. Estradiol affected neither the number of α1 sites in frontal cortex nor the affinity of [3H]prazosin binding in any brain region sampled. Estradiol had no effect on [3H]idazoxan (α2) or [3H]dihydroalprenolol (β) binding in hypothalamus, preoptic area or cortex. Progesterone reversed estradiol elevation of prazosin binding in preoptic area but had no other measurable effects on any noradrenergic receptor binding when given alone or in combination with estradiol. Neither estradiol nor progesterone altered binding of radiolabeled antagonists when they were included in the in vitro incubation mixture. These data suggest that the increased α1 receptor augmentation of cAMP accumulation seen in hypothalamic and preoptic area slices from estradiol-treated rats is correlated with increased α1 receptor number. In contrast, estradiol attenuation of β receptor function and progesterone depression of norepinephrine-stimulated cAMP generation in slices from estradiol-treated females is not correlated with downregulation of any noradrenergic receptor subtype." @default.
• W2080867526 created "2016-06-24" @default.
• W2080867526 creator A5035809946 @default.
• W2080867526 creator A5040209391 @default.
• W2080867526 date "1990-01-01" @default.
• W2080867526 modified "2023-09-23" @default.
• W2080867526 title "Estradiol regulates the number of α1 but not β or α2 noradrenergic receptors in hypothalamus of female rats" @default.
• W2080867526 cites W1775749144 @default.
• W2080867526 cites W1978966327 @default.
• W2080867526 cites W1981143995 @default.
• W2080867526 cites W1981558160 @default.
• W2080867526 cites W1987336505 @default.
• W2080867526 cites W1991519783 @default.
• W2080867526 cites W1992099554 @default.
• W2080867526 cites W1999855858 @default.
• W2080867526 cites W2002896245 @default.
• W2080867526 cites W2003441289 @default.
• W2080867526 cites W2003930428 @default.
• W2080867526 cites W2014253965 @default.
• W2080867526 cites W2016912445 @default.
• W2080867526 cites W2018736470 @default.
• W2080867526 cites W2023128313 @default.
• W2080867526 cites W2029012757 @default.
• W2080867526 cites W2031062785 @default.
• W2080867526 cites W2041783261 @default.
• W2080867526 cites W2042377179 @default.
• W2080867526 cites W2043813981 @default.
• W2080867526 cites W2046527332 @default.
• W2080867526 cites W2047211858 @default.
• W2080867526 cites W2060519500 @default.
• W2080867526 cites W2062352146 @default.
• W2080867526 cites W2073637372 @default.
• W2080867526 cites W2076778666 @default.
• W2080867526 cites W2078461774 @default.
• W2080867526 cites W2088115099 @default.
• W2080867526 cites W2088802774 @default.
• W2080867526 cites W2093463989 @default.
• W2080867526 doi "https://doi.org/10.1016/0197-0186(90)90117-c" @default.
• W2080867526 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20504534" @default.
• W2080867526 hasPublicationYear "1990" @default.
• W2080867526 type Work @default.
• W2080867526 sameAs 2080867526 @default.
• W2080867526 citedByCount "24" @default.
• W2080867526 countsByYear W20808675262014 @default.
• W2080867526 crossrefType "journal-article" @default.
• W2080867526 hasAuthorship W2080867526A5035809946 @default.
• W2080867526 hasAuthorship W2080867526A5040209391 @default.
• W2080867526 hasConcept C126322002 @default.
• W2080867526 hasConcept C134018914 @default.
• W2080867526 hasConcept C170493617 @default.
• W2080867526 hasConcept C185592680 @default.
• W2080867526 hasConcept C2776451244 @default.
• W2080867526 hasConcept C2776885963 @default.
• W2080867526 hasConcept C2777003273 @default.
• W2080867526 hasConcept C2778438532 @default.
• W2080867526 hasConcept C2778514916 @default.
• W2080867526 hasConcept C2778938600 @default.
• W2080867526 hasConcept C2780648677 @default.
• W2080867526 hasConcept C2780939551 @default.
• W2080867526 hasConcept C513476851 @default.
• W2080867526 hasConcept C58732023 @default.
• W2080867526 hasConcept C71924100 @default.
• W2080867526 hasConcept C86803240 @default.
• W2080867526 hasConceptScore W2080867526C126322002 @default.
• W2080867526 hasConceptScore W2080867526C134018914 @default.
• W2080867526 hasConceptScore W2080867526C170493617 @default.
• W2080867526 hasConceptScore W2080867526C185592680 @default.
• W2080867526 hasConceptScore W2080867526C2776451244 @default.
• W2080867526 hasConceptScore W2080867526C2776885963 @default.
• W2080867526 hasConceptScore W2080867526C2777003273 @default.
• W2080867526 hasConceptScore W2080867526C2778438532 @default.
• W2080867526 hasConceptScore W2080867526C2778514916 @default.
• W2080867526 hasConceptScore W2080867526C2778938600 @default.
• W2080867526 hasConceptScore W2080867526C2780648677 @default.
• W2080867526 hasConceptScore W2080867526C2780939551 @default.
• W2080867526 hasConceptScore W2080867526C513476851 @default.
• W2080867526 hasConceptScore W2080867526C58732023 @default.
• W2080867526 hasConceptScore W2080867526C71924100 @default.
• W2080867526 hasConceptScore W2080867526C86803240 @default.
• W2080867526 hasIssue "1" @default.
• W2080867526 hasLocation W20808675261 @default.
• W2080867526 hasLocation W20808675262 @default.
• W2080867526 hasOpenAccess W2080867526 @default.
• W2080867526 hasPrimaryLocation W20808675261 @default.
• W2080867526 hasRelatedWork W1965743830 @default.
• W2080867526 hasRelatedWork W1974059066 @default.
• W2080867526 hasRelatedWork W1979410451 @default.
• W2080867526 hasRelatedWork W1980471661 @default.
• W2080867526 hasRelatedWork W1983321239 @default.
• W2080867526 hasRelatedWork W2022857682 @default.
• W2080867526 hasRelatedWork W2029739536 @default.
• W2080867526 hasRelatedWork W2061201600 @default.
• W2080867526 hasRelatedWork W2080867526 @default.
• W2080867526 hasRelatedWork W2315166476 @default.
• W2080867526 hasVolume "16" @default.
• W2080867526 isParatext "false" @default.
• W2080867526 isRetracted "false" @default.
• W2080867526 magId "2080867526" @default.

• next