FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080912674> ?p ?o ?g. }

• W2080912674 endingPage "709" @default.
• W2080912674 startingPage "702" @default.
• W2080912674 abstract "The infectious burden leading to immune activation can vary between different populations and lead to various immune dysfunctions. We compared the effect of immune activation on apoptosis and T cell function in HIV uninfected individuals from Nairobi, Kenya (n=34), and Winnipeg, Canada (n=10). Women from Nairobi had a significantly greater number of CD8+ T cells expressing the activation markers CD38 and HLA DR. Kenyan women also had significantly higher levels of CTLA-4+ CD4 and CD8+ T cells, and reduced levels of CD28+ CD8+ cells. Levels of CD95+ CD4+ T cells were higher in Kenyan women and, correspondingly, showed higher levels of spontaneous apoptosis. Kenyan women also demonstrated hyper-responsiveness to T cell activation as assessed by interferon gamma production. This study demonstrates that in a population of Kenyan women with high levels of T cell activation, there were also elevated levels of T cell apoptotic death and hyper-responsiveness. These differences may influence the efficacy of immune responses to pathogens and must be considered when testing candidate vaccines." @default.
• W2080912674 created "2016-06-24" @default.
• W2080912674 creator A5004563927 @default.
• W2080912674 creator A5016623339 @default.
• W2080912674 creator A5032683070 @default.
• W2080912674 creator A5039284526 @default.
• W2080912674 creator A5040529839 @default.
• W2080912674 creator A5042629291 @default.
• W2080912674 creator A5078709209 @default.
• W2080912674 creator A5079876623 @default.
• W2080912674 date "2004-11-01" @default.
• W2080912674 modified "2023-10-16" @default.
• W2080912674 title "Elevation of Immune Activation in Kenyan Women is Associated with Alterations in Immune Function: Implications for Vaccine Development" @default.
• W2080912674 cites W1608236599 @default.
• W2080912674 cites W1971184222 @default.
• W2080912674 cites W1973508574 @default.
• W2080912674 cites W1978141065 @default.
• W2080912674 cites W1979744973 @default.
• W2080912674 cites W1985591364 @default.
• W2080912674 cites W1986097902 @default.
• W2080912674 cites W1986512614 @default.
• W2080912674 cites W1996958965 @default.
• W2080912674 cites W2014688243 @default.
• W2080912674 cites W2027188714 @default.
• W2080912674 cites W2033607574 @default.
• W2080912674 cites W2044268404 @default.
• W2080912674 cites W2053898412 @default.
• W2080912674 cites W2063662982 @default.
• W2080912674 cites W2064130642 @default.
• W2080912674 cites W2066996164 @default.
• W2080912674 cites W2083295790 @default.
• W2080912674 cites W2106970870 @default.
• W2080912674 cites W2124515177 @default.
• W2080912674 cites W2149951876 @default.
• W2080912674 cites W2153811068 @default.
• W2080912674 cites W2157134016 @default.
• W2080912674 cites W2159578627 @default.
• W2080912674 cites W2166986372 @default.
• W2080912674 cites W2171323752 @default.
• W2080912674 cites W2327430468 @default.
• W2080912674 cites W2397690158 @default.
• W2080912674 doi "https://doi.org/10.1007/s10875-004-6238-1" @default.
• W2080912674 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15622455" @default.
• W2080912674 hasPublicationYear "2004" @default.
• W2080912674 type Work @default.
• W2080912674 sameAs 2080912674 @default.
• W2080912674 citedByCount "19" @default.
• W2080912674 countsByYear W20809126742012 @default.
• W2080912674 countsByYear W20809126742014 @default.
• W2080912674 countsByYear W20809126742015 @default.
• W2080912674 countsByYear W20809126742016 @default.
• W2080912674 countsByYear W20809126742018 @default.
• W2080912674 countsByYear W20809126742021 @default.
• W2080912674 crossrefType "journal-article" @default.
• W2080912674 hasAuthorship W2080912674A5004563927 @default.
• W2080912674 hasAuthorship W2080912674A5016623339 @default.
• W2080912674 hasAuthorship W2080912674A5032683070 @default.
• W2080912674 hasAuthorship W2080912674A5039284526 @default.
• W2080912674 hasAuthorship W2080912674A5040529839 @default.
• W2080912674 hasAuthorship W2080912674A5042629291 @default.
• W2080912674 hasAuthorship W2080912674A5078709209 @default.
• W2080912674 hasAuthorship W2080912674A5079876623 @default.
• W2080912674 hasBestOaLocation W20809126741 @default.
• W2080912674 hasConcept C10205521 @default.
• W2080912674 hasConcept C148125776 @default.
• W2080912674 hasConcept C159912055 @default.
• W2080912674 hasConcept C167672396 @default.
• W2080912674 hasConcept C187651312 @default.
• W2080912674 hasConcept C18903297 @default.
• W2080912674 hasConcept C203014093 @default.
• W2080912674 hasConcept C2776090121 @default.
• W2080912674 hasConcept C28328180 @default.
• W2080912674 hasConcept C86803240 @default.
• W2080912674 hasConcept C8891405 @default.
• W2080912674 hasConcept C95444343 @default.
• W2080912674 hasConceptScore W2080912674C10205521 @default.
• W2080912674 hasConceptScore W2080912674C148125776 @default.
• W2080912674 hasConceptScore W2080912674C159912055 @default.
• W2080912674 hasConceptScore W2080912674C167672396 @default.
• W2080912674 hasConceptScore W2080912674C187651312 @default.
• W2080912674 hasConceptScore W2080912674C18903297 @default.
• W2080912674 hasConceptScore W2080912674C203014093 @default.
• W2080912674 hasConceptScore W2080912674C2776090121 @default.
• W2080912674 hasConceptScore W2080912674C28328180 @default.
• W2080912674 hasConceptScore W2080912674C86803240 @default.
• W2080912674 hasConceptScore W2080912674C8891405 @default.
• W2080912674 hasConceptScore W2080912674C95444343 @default.
• W2080912674 hasIssue "6" @default.
• W2080912674 hasLocation W20809126741 @default.
• W2080912674 hasLocation W20809126742 @default.
• W2080912674 hasOpenAccess W2080912674 @default.
• W2080912674 hasPrimaryLocation W20809126741 @default.
• W2080912674 hasRelatedWork W1981908249 @default.
• W2080912674 hasRelatedWork W2040212555 @default.
• W2080912674 hasRelatedWork W2057057794 @default.
• W2080912674 hasRelatedWork W2115516753 @default.
• W2080912674 hasRelatedWork W2434372360 @default.
• W2080912674 hasRelatedWork W2463625467 @default.

• next