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• W2080930178 abstract "A new depsipeptide, cyanopeptolin 963 A (1), was isolated from an axenic strain of the toxic freshwater cyanobacterium Microcystis PCC 7806. The structure of this compound was elucidated by chemical and spectroscopic analyses, including high-resolution ESI-FTICR-MS, 2-D NMR, and GC-MS of the hydrolysate. The major structural difference compared to previously characterized cyanopeptolins of this strain is the replacement of the basic amino acid in position 3 by L-tyrosine. Compound 1 displayed inhibitory activity against chymotrypsin with an IC50 value of 0.9 microM." @default.
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• W2080930178 date "2004-09-16" @default.
• W2080930178 modified "2023-10-18" @default.
• W2080930178 title "Cyanopeptolin 963A, a Chymotrypsin Inhibitor of <i>Microcystis</i> PCC 7806" @default.
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• W2080930178 doi "https://doi.org/10.1021/np049828f" @default.
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