Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080945906> ?p ?o ?g. }
- W2080945906 endingPage "662" @default.
- W2080945906 startingPage "656" @default.
- W2080945906 abstract "This study evaluated the effect of fenoldopam, a selective dopamine (DA1) agonist, on renal blood flow and renal tubular function following renal ischemia induced by suprarenal aortic cross-clamping. Twenty anesthetized research pigs received either fenoldopam (10 micro g/kg/min; n = 10) or saline ( n = 10) beginning 20 min before suprarenal aortic cross-clamping and continuing for 20 min after clamp release, for a total infusion time of 160 min (120-min cross-clamp). Recordings of renal blood flow, mean arterial pressure, and heart rate were taken at baseline, during cross-clamping, and immediately postclamp. Ischemic renal injury was evaluated by serum creatinine and by histologic grading of acute tubular necrosis. Treatment with fenoldopam increased renal blood flow in comparison to that in the control group ( p = 0.03). The mean creatinine increase from baseline at 6 hr and 18 hr after cross-clamp removal for the fenoldopam-treated group was significantly less than that in the control group ( p < 0.001). On histologic evaluation, the mean score for the degree of tubular necrosis was significantly higher in the control group ( p = 0.02), indicating less derangement of tubular morphology in the fenoldopam group. This study demonstrated that the intraoperative use of a continuous infusion of fenoldopam during suprarenal aortic cross-clamping results in increased renal blood flow, less postoperative rise in creatinine, and better preservation of tubular histology in the pig model." @default.
- W2080945906 created "2016-06-24" @default.
- W2080945906 creator A5014958638 @default.
- W2080945906 creator A5016061416 @default.
- W2080945906 creator A5019520546 @default.
- W2080945906 creator A5038552892 @default.
- W2080945906 creator A5039131664 @default.
- W2080945906 creator A5042378459 @default.
- W2080945906 creator A5048839449 @default.
- W2080945906 creator A5068647425 @default.
- W2080945906 creator A5074207222 @default.
- W2080945906 creator A5076454053 @default.
- W2080945906 creator A5090109087 @default.
- W2080945906 date "2003-11-01" @default.
- W2080945906 modified "2023-09-27" @default.
- W2080945906 title "The Effects of Intraoperative Fenoldopam on Renal Blood Flow and Tubular Function following Suprarenal Aortic Cross-clamping" @default.
- W2080945906 cites W175395351 @default.
- W2080945906 cites W1967930071 @default.
- W2080945906 cites W1973760111 @default.
- W2080945906 cites W1975103942 @default.
- W2080945906 cites W1978087690 @default.
- W2080945906 cites W1990632655 @default.
- W2080945906 cites W1996654846 @default.
- W2080945906 cites W2003093519 @default.
- W2080945906 cites W2013534682 @default.
- W2080945906 cites W2017320443 @default.
- W2080945906 cites W2029705906 @default.
- W2080945906 cites W2030682946 @default.
- W2080945906 cites W2034841074 @default.
- W2080945906 cites W2042786525 @default.
- W2080945906 cites W2057159770 @default.
- W2080945906 cites W2058382167 @default.
- W2080945906 cites W2062843237 @default.
- W2080945906 cites W2066087866 @default.
- W2080945906 cites W2117857718 @default.
- W2080945906 cites W2132979483 @default.
- W2080945906 cites W2152229652 @default.
- W2080945906 cites W2172136015 @default.
- W2080945906 cites W2318093943 @default.
- W2080945906 cites W2330263411 @default.
- W2080945906 cites W2399890791 @default.
- W2080945906 cites W2409369851 @default.
- W2080945906 cites W2412772982 @default.
- W2080945906 doi "https://doi.org/10.1007/s10016-003-0067-1" @default.
- W2080945906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14569432" @default.
- W2080945906 hasPublicationYear "2003" @default.
- W2080945906 type Work @default.
- W2080945906 sameAs 2080945906 @default.
- W2080945906 citedByCount "27" @default.
- W2080945906 countsByYear W20809459062013 @default.
- W2080945906 countsByYear W20809459062014 @default.
- W2080945906 countsByYear W20809459062016 @default.
- W2080945906 countsByYear W20809459062017 @default.
- W2080945906 countsByYear W20809459062019 @default.
- W2080945906 countsByYear W20809459062020 @default.
- W2080945906 crossrefType "journal-article" @default.
- W2080945906 hasAuthorship W2080945906A5014958638 @default.
- W2080945906 hasAuthorship W2080945906A5016061416 @default.
- W2080945906 hasAuthorship W2080945906A5019520546 @default.
- W2080945906 hasAuthorship W2080945906A5038552892 @default.
- W2080945906 hasAuthorship W2080945906A5039131664 @default.
- W2080945906 hasAuthorship W2080945906A5042378459 @default.
- W2080945906 hasAuthorship W2080945906A5048839449 @default.
- W2080945906 hasAuthorship W2080945906A5068647425 @default.
- W2080945906 hasAuthorship W2080945906A5074207222 @default.
- W2080945906 hasAuthorship W2080945906A5076454053 @default.
- W2080945906 hasAuthorship W2080945906A5090109087 @default.
- W2080945906 hasConcept C126322002 @default.
- W2080945906 hasConcept C126894567 @default.
- W2080945906 hasConcept C142225936 @default.
- W2080945906 hasConcept C158846371 @default.
- W2080945906 hasConcept C159641895 @default.
- W2080945906 hasConcept C170493617 @default.
- W2080945906 hasConcept C2776452961 @default.
- W2080945906 hasConcept C2777350860 @default.
- W2080945906 hasConcept C2777953023 @default.
- W2080945906 hasConcept C2778938600 @default.
- W2080945906 hasConcept C2779867896 @default.
- W2080945906 hasConcept C2780091579 @default.
- W2080945906 hasConcept C2780306776 @default.
- W2080945906 hasConcept C2781073237 @default.
- W2080945906 hasConcept C42219234 @default.
- W2080945906 hasConcept C71924100 @default.
- W2080945906 hasConcept C84393581 @default.
- W2080945906 hasConceptScore W2080945906C126322002 @default.
- W2080945906 hasConceptScore W2080945906C126894567 @default.
- W2080945906 hasConceptScore W2080945906C142225936 @default.
- W2080945906 hasConceptScore W2080945906C158846371 @default.
- W2080945906 hasConceptScore W2080945906C159641895 @default.
- W2080945906 hasConceptScore W2080945906C170493617 @default.
- W2080945906 hasConceptScore W2080945906C2776452961 @default.
- W2080945906 hasConceptScore W2080945906C2777350860 @default.
- W2080945906 hasConceptScore W2080945906C2777953023 @default.
- W2080945906 hasConceptScore W2080945906C2778938600 @default.
- W2080945906 hasConceptScore W2080945906C2779867896 @default.
- W2080945906 hasConceptScore W2080945906C2780091579 @default.
- W2080945906 hasConceptScore W2080945906C2780306776 @default.
- W2080945906 hasConceptScore W2080945906C2781073237 @default.