Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080955010> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2080955010 endingPage "586" @default.
- W2080955010 startingPage "577" @default.
- W2080955010 abstract "Some aspects of the humoral response in trypanotolerant C57B1 mice and susceptible A/J mice were investigated to determine the possible basis of trypanotolerance. When the hepatic uptake of 75Se-labelled T. congolense by infected mice was measured as an index of antibody production, it was found that only C57B1 mice could remove circulating labelled parasites, this ability persisting for several weeks after infection. Estimation of the immunoglobulin concentrations in both strains of mice showed that C57B1 mice developed a pronounced IgM response during the first parasitaemic wave, while A/J mice did not. Over the same period the IgM concentrations in C57B1 mice initially fell, but recovered at the time of peak parasitaemia. In contrast, A/J mice showed a continual fall in total IgG concentrations in the circulation until death 10 days after infection. Finally, it was shown that during the initial rising parasitaemia, the plaque forming cell responses of both strains of mice to sheep red blood cells were normal indicating that neither strain of mice was immunosuppressed. Also, A/J mice vaccinated with irradiated T. brucei on day 4 and C57B1 mice vaccinated either on day 4 or day 60 of a T. congolense infection were able to mount an effective immune response to the vaccine, as judged by the hepatic uptake of radiolabelled parasites. All of the results indicate that the trypanotolerance of C57B1 mice depends, at least in part, on their more efficient antibody response." @default.
- W2080955010 created "2016-06-24" @default.
- W2080955010 creator A5005164269 @default.
- W2080955010 creator A5030686300 @default.
- W2080955010 creator A5058818146 @default.
- W2080955010 creator A5080258144 @default.
- W2080955010 creator A5091012347 @default.
- W2080955010 date "1983-11-01" @default.
- W2080955010 modified "2023-09-27" @default.
- W2080955010 title "Immune mechanisms in C57B1 mice genetically resistant to Trypanosoma congolense infection. II. Aspects of the humoral response" @default.
- W2080955010 cites W1861329585 @default.
- W2080955010 cites W1970144610 @default.
- W2080955010 cites W1992760440 @default.
- W2080955010 cites W2037684525 @default.
- W2080955010 cites W2046221177 @default.
- W2080955010 cites W2061038306 @default.
- W2080955010 cites W2089666915 @default.
- W2080955010 cites W2409441911 @default.
- W2080955010 cites W2414952368 @default.
- W2080955010 cites W4246491488 @default.
- W2080955010 cites W4249661838 @default.
- W2080955010 doi "https://doi.org/10.1111/j.1365-3024.1983.tb00774.x" @default.
- W2080955010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6657296" @default.
- W2080955010 hasPublicationYear "1983" @default.
- W2080955010 type Work @default.
- W2080955010 sameAs 2080955010 @default.
- W2080955010 citedByCount "12" @default.
- W2080955010 countsByYear W20809550102012 @default.
- W2080955010 countsByYear W20809550102013 @default.
- W2080955010 crossrefType "journal-article" @default.
- W2080955010 hasAuthorship W2080955010A5005164269 @default.
- W2080955010 hasAuthorship W2080955010A5030686300 @default.
- W2080955010 hasAuthorship W2080955010A5058818146 @default.
- W2080955010 hasAuthorship W2080955010A5080258144 @default.
- W2080955010 hasAuthorship W2080955010A5091012347 @default.
- W2080955010 hasConcept C159047783 @default.
- W2080955010 hasConcept C159654299 @default.
- W2080955010 hasConcept C203014093 @default.
- W2080955010 hasConcept C2776553844 @default.
- W2080955010 hasConcept C2778143080 @default.
- W2080955010 hasConcept C2779341262 @default.
- W2080955010 hasConcept C2779549974 @default.
- W2080955010 hasConcept C2780898057 @default.
- W2080955010 hasConcept C3018913218 @default.
- W2080955010 hasConcept C86803240 @default.
- W2080955010 hasConcept C8891405 @default.
- W2080955010 hasConceptScore W2080955010C159047783 @default.
- W2080955010 hasConceptScore W2080955010C159654299 @default.
- W2080955010 hasConceptScore W2080955010C203014093 @default.
- W2080955010 hasConceptScore W2080955010C2776553844 @default.
- W2080955010 hasConceptScore W2080955010C2778143080 @default.
- W2080955010 hasConceptScore W2080955010C2779341262 @default.
- W2080955010 hasConceptScore W2080955010C2779549974 @default.
- W2080955010 hasConceptScore W2080955010C2780898057 @default.
- W2080955010 hasConceptScore W2080955010C3018913218 @default.
- W2080955010 hasConceptScore W2080955010C86803240 @default.
- W2080955010 hasConceptScore W2080955010C8891405 @default.
- W2080955010 hasIssue "6" @default.
- W2080955010 hasLocation W20809550101 @default.
- W2080955010 hasLocation W20809550102 @default.
- W2080955010 hasOpenAccess W2080955010 @default.
- W2080955010 hasPrimaryLocation W20809550101 @default.
- W2080955010 hasRelatedWork W122790948 @default.
- W2080955010 hasRelatedWork W1572283981 @default.
- W2080955010 hasRelatedWork W1655532523 @default.
- W2080955010 hasRelatedWork W191183980 @default.
- W2080955010 hasRelatedWork W1966870776 @default.
- W2080955010 hasRelatedWork W1982142138 @default.
- W2080955010 hasRelatedWork W2039006121 @default.
- W2080955010 hasRelatedWork W2094743478 @default.
- W2080955010 hasRelatedWork W2411114470 @default.
- W2080955010 hasRelatedWork W4200563690 @default.
- W2080955010 hasVolume "5" @default.
- W2080955010 isParatext "false" @default.
- W2080955010 isRetracted "false" @default.
- W2080955010 magId "2080955010" @default.
- W2080955010 workType "article" @default.