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- W2080963609 abstract "Thioridazine was recently reported to cause a specific form of ventricular tachyarrhythmia termed “torsade de pointes” (Kemper et al. 1983; Liberatore and Robinson 1984; Plugelman et al. 1985), which may progress to sustained ventricular tachycardia or ventricular fibrillation and cardiac arrest (Smith and Gallagher 1980). It was subsequently suggested that torsade de pointes may be a cause of sudden unexplained death associated with neuroleptic drug therapy (Liberatore and Robinson 1984). In this report, we describe a patient in whom a preexisting prolonged QT interval led to the development of potentially fatal ventricular tachyarrhythmia of torsade de pointes during low-dose and short-term therapy with thioridazine. The recurrent ventricular tachyarrhythmia was exacerbated by lidocaine hydrochloride and procainamide hydrochloride therapy, but it was effectively controlled by cardiac pacing." @default.
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- W2080963609 date "1987-01-01" @default.
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- W2080963609 title "Iatrogenic torsade de pointes induced by thioridazine" @default.
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- W2080963609 doi "https://doi.org/10.1016/0006-3223(87)90135-1" @default.
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