Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080981606> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2080981606 endingPage "55" @default.
- W2080981606 startingPage "47" @default.
- W2080981606 abstract "Physostigmine salicylate was incorporated in a soybean injectable emulsion in an attempt to control the drug release from the emulsion. In vitro examination of the physicochemical properties of the emulsions revealed that a mixture of an anionic (phospholipid) and non-ionic surfactant (Pluronic) was required to prepare stable physostigmine emulsions. Variation in concentration of either the anionic or non-ionic emulsifier decreased the mean droplet size while the zeta potential did not show any clear correlation with increasing phospholipid concentration but decreased, reached a plateau and fell again with increasing Pluronic concentration. In the presence of physostigmine salicylate. instability was introduced which changed the profile of zeta potential dependency on phospholipids and Pluronic concentrations. Zeta potential increased with physostigmine concentration as a result of increasing ionization of various polar groups at the oil-water droplet interface. Moreover, physostigmine incorporated in the emulsion was protected from its aqueous decomposition and remained intact. Stable physostigmine emulsions preserved over long periods of time were obtained using appropriate experimental conditions probably as a result of optimization of effects due to surface potential increase, droplet size reduction and formation of a resistant close-packed interfacial mixed film. which confers steric stabilization to the dispersed droplets." @default.
- W2080981606 created "2016-06-24" @default.
- W2080981606 creator A5044592411 @default.
- W2080981606 creator A5072115967 @default.
- W2080981606 creator A5089887580 @default.
- W2080981606 date "1986-05-01" @default.
- W2080981606 modified "2023-10-16" @default.
- W2080981606 title "Physostigmine emulsion: a new injectable controlled release delivery system" @default.
- W2080981606 cites W1985697126 @default.
- W2080981606 cites W1987062784 @default.
- W2080981606 cites W1988400834 @default.
- W2080981606 cites W2020435088 @default.
- W2080981606 cites W2034518103 @default.
- W2080981606 cites W2036818412 @default.
- W2080981606 cites W2048085154 @default.
- W2080981606 cites W2048213635 @default.
- W2080981606 cites W2066718115 @default.
- W2080981606 cites W2075635948 @default.
- W2080981606 cites W2088361764 @default.
- W2080981606 cites W2159282771 @default.
- W2080981606 cites W2166778989 @default.
- W2080981606 cites W2171211821 @default.
- W2080981606 cites W2313430342 @default.
- W2080981606 cites W2322159557 @default.
- W2080981606 cites W2333854607 @default.
- W2080981606 doi "https://doi.org/10.1016/0378-5173(86)90134-1" @default.
- W2080981606 hasPublicationYear "1986" @default.
- W2080981606 type Work @default.
- W2080981606 sameAs 2080981606 @default.
- W2080981606 citedByCount "44" @default.
- W2080981606 countsByYear W20809816062012 @default.
- W2080981606 countsByYear W20809816062013 @default.
- W2080981606 countsByYear W20809816062014 @default.
- W2080981606 countsByYear W20809816062015 @default.
- W2080981606 countsByYear W20809816062016 @default.
- W2080981606 countsByYear W20809816062017 @default.
- W2080981606 countsByYear W20809816062018 @default.
- W2080981606 countsByYear W20809816062020 @default.
- W2080981606 crossrefType "journal-article" @default.
- W2080981606 hasAuthorship W2080981606A5044592411 @default.
- W2080981606 hasAuthorship W2080981606A5072115967 @default.
- W2080981606 hasAuthorship W2080981606A5089887580 @default.
- W2080981606 hasConcept C101335993 @default.
- W2080981606 hasConcept C127413603 @default.
- W2080981606 hasConcept C155672457 @default.
- W2080981606 hasConcept C15920480 @default.
- W2080981606 hasConcept C178790620 @default.
- W2080981606 hasConcept C185592680 @default.
- W2080981606 hasConcept C2775910092 @default.
- W2080981606 hasConcept C2776663719 @default.
- W2080981606 hasConcept C2778123984 @default.
- W2080981606 hasConcept C42360764 @default.
- W2080981606 hasConcept C43617362 @default.
- W2080981606 hasConcept C521977710 @default.
- W2080981606 hasConcept C71924100 @default.
- W2080981606 hasConcept C86181022 @default.
- W2080981606 hasConcept C98274493 @default.
- W2080981606 hasConceptScore W2080981606C101335993 @default.
- W2080981606 hasConceptScore W2080981606C127413603 @default.
- W2080981606 hasConceptScore W2080981606C155672457 @default.
- W2080981606 hasConceptScore W2080981606C15920480 @default.
- W2080981606 hasConceptScore W2080981606C178790620 @default.
- W2080981606 hasConceptScore W2080981606C185592680 @default.
- W2080981606 hasConceptScore W2080981606C2775910092 @default.
- W2080981606 hasConceptScore W2080981606C2776663719 @default.
- W2080981606 hasConceptScore W2080981606C2778123984 @default.
- W2080981606 hasConceptScore W2080981606C42360764 @default.
- W2080981606 hasConceptScore W2080981606C43617362 @default.
- W2080981606 hasConceptScore W2080981606C521977710 @default.
- W2080981606 hasConceptScore W2080981606C71924100 @default.
- W2080981606 hasConceptScore W2080981606C86181022 @default.
- W2080981606 hasConceptScore W2080981606C98274493 @default.
- W2080981606 hasIssue "1" @default.
- W2080981606 hasLocation W20809816061 @default.
- W2080981606 hasOpenAccess W2080981606 @default.
- W2080981606 hasPrimaryLocation W20809816061 @default.
- W2080981606 hasRelatedWork W1966189628 @default.
- W2080981606 hasRelatedWork W1984315799 @default.
- W2080981606 hasRelatedWork W2080981606 @default.
- W2080981606 hasRelatedWork W2170920551 @default.
- W2080981606 hasRelatedWork W2352333521 @default.
- W2080981606 hasRelatedWork W2402916833 @default.
- W2080981606 hasRelatedWork W2443769454 @default.
- W2080981606 hasRelatedWork W3033059819 @default.
- W2080981606 hasRelatedWork W3205937679 @default.
- W2080981606 hasRelatedWork W4211249123 @default.
- W2080981606 hasVolume "30" @default.
- W2080981606 isParatext "false" @default.
- W2080981606 isRetracted "false" @default.
- W2080981606 magId "2080981606" @default.
- W2080981606 workType "article" @default.