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- W208098247 abstract "When modeling the respiratory control system, it is useful to know the inherent noise in the variables of interest, such as the arterial PCO2 and the sensitivity of the hypercapnic ventilatory response (HCVR). These variables can be greatly affected by behavioral and environmental conditions including fluctuations in arousal level, emotion, cognitive activity, subject-experimenter interaction, light, noise and temperature. For instance, even when in an ostensible steady-state, merely opening one’s eyes results in systematic increases in breathing frequency, ventilation and HCVR slope (reviewed by Shea1). In addition, challenges to the respiratory control system (e.g., added loads, hypoxia or hypercapnia) can result in adaptation such that subsequent measurements are affected by prior measurements (e.g., Powell et al2). Furthermore there can be non-physiological variability that is intrinsic to the measurement technique itself (e.g., instability of sensors). Overall, influences from behaviors, arousal, the environment, adaptation and the measurement technique contribute to the ‘noise’ in the measured data." @default.
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- W208098247 title "Explained and Unexplained Variability of CO2-Sensitivity in Humans" @default.
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