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- W2080986001 abstract "The predictive value of the dexamethasone suppression test (DST) was evaluated in two consecutive double-blind, placebo-controlled trials evaluating 61 depressed inpatients randomized to either one of two drugs, sertraline or oxaprotiline, or placebo over a 4-week clinical trial. For 30 patients who completed at least 3 weeks of double-blind treatment on either drug, the initial DST was not predictive of response to drug treatment. For the 17 patients who completed at least 3 weeks of double-blind treatment on placebo, the presence of a positive DST predicted a statistically significantly poorer response to placebo as opposed to a negative DST. These preliminary findings suggest that for depressed individuals who present with a positive DST, remission without active medication is less likely and somatic treatment should be considered." @default.
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- W2080986001 date "1986-10-01" @default.
- W2080986001 modified "2023-10-17" @default.
- W2080986001 title "The Dexamethasone Suppression Test and Response to Placebo" @default.
- W2080986001 doi "https://doi.org/10.1097/00004714-198610000-00005" @default.
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