Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080990079> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2080990079 endingPage "360" @default.
- W2080990079 startingPage "355" @default.
- W2080990079 abstract "A homogeneous set of low-molecular weight heparins, chemically modified to yield different degrees of sulfation, were investigated for their ability to interfere with the antithrombin (AT)-factor Xa (FXa) interaction process in the presence or absence of physiological concentrations of calcium ions. The heparin-AT dissociation constants were not appreciably affected by the presence of the metal ion, whereas the catalytic process was strongly dependent on Ca 2+. Our data suggest that AT binding to heparin represents the main factor driving the FXa inhibition process. In addition, the presence of the metal ion is likely to mask favorable AT- heparin ionic contacts occurring with the highly sulfated material. These results help in assessing proper structure-activity relationships for glycosaminoglycans, a multitarget family of biologically active compounds." @default.
- W2080990079 created "2016-06-24" @default.
- W2080990079 creator A5001638640 @default.
- W2080990079 creator A5044720565 @default.
- W2080990079 creator A5054049326 @default.
- W2080990079 creator A5075876145 @default.
- W2080990079 creator A5084282500 @default.
- W2080990079 date "2002-01-01" @default.
- W2080990079 modified "2023-09-26" @default.
- W2080990079 title "Effects of Calcium Ions on the Interactions between Antithrombin and Factor Xa Mediated by Variously Sulfated, Semisynthetic Low-Molecular-Weight Heparins" @default.
- W2080990079 doi "https://doi.org/10.1055/s-2002-34304" @default.
- W2080990079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12244482" @default.
- W2080990079 hasPublicationYear "2002" @default.
- W2080990079 type Work @default.
- W2080990079 sameAs 2080990079 @default.
- W2080990079 citedByCount "1" @default.
- W2080990079 countsByYear W20809900792023 @default.
- W2080990079 crossrefType "journal-article" @default.
- W2080990079 hasAuthorship W2080990079A5001638640 @default.
- W2080990079 hasAuthorship W2080990079A5044720565 @default.
- W2080990079 hasAuthorship W2080990079A5054049326 @default.
- W2080990079 hasAuthorship W2080990079A5075876145 @default.
- W2080990079 hasAuthorship W2080990079A5084282500 @default.
- W2080990079 hasConcept C102931765 @default.
- W2080990079 hasConcept C12554922 @default.
- W2080990079 hasConcept C134121241 @default.
- W2080990079 hasConcept C153074725 @default.
- W2080990079 hasConcept C155138218 @default.
- W2080990079 hasConcept C170493617 @default.
- W2080990079 hasConcept C178790620 @default.
- W2080990079 hasConcept C179104552 @default.
- W2080990079 hasConcept C185592680 @default.
- W2080990079 hasConcept C191897082 @default.
- W2080990079 hasConcept C192562407 @default.
- W2080990079 hasConcept C199164860 @default.
- W2080990079 hasConcept C2776884760 @default.
- W2080990079 hasConcept C2777557582 @default.
- W2080990079 hasConcept C2779026020 @default.
- W2080990079 hasConcept C519063684 @default.
- W2080990079 hasConcept C544153396 @default.
- W2080990079 hasConcept C55493867 @default.
- W2080990079 hasConcept C74998103 @default.
- W2080990079 hasConcept C86803240 @default.
- W2080990079 hasConceptScore W2080990079C102931765 @default.
- W2080990079 hasConceptScore W2080990079C12554922 @default.
- W2080990079 hasConceptScore W2080990079C134121241 @default.
- W2080990079 hasConceptScore W2080990079C153074725 @default.
- W2080990079 hasConceptScore W2080990079C155138218 @default.
- W2080990079 hasConceptScore W2080990079C170493617 @default.
- W2080990079 hasConceptScore W2080990079C178790620 @default.
- W2080990079 hasConceptScore W2080990079C179104552 @default.
- W2080990079 hasConceptScore W2080990079C185592680 @default.
- W2080990079 hasConceptScore W2080990079C191897082 @default.
- W2080990079 hasConceptScore W2080990079C192562407 @default.
- W2080990079 hasConceptScore W2080990079C199164860 @default.
- W2080990079 hasConceptScore W2080990079C2776884760 @default.
- W2080990079 hasConceptScore W2080990079C2777557582 @default.
- W2080990079 hasConceptScore W2080990079C2779026020 @default.
- W2080990079 hasConceptScore W2080990079C519063684 @default.
- W2080990079 hasConceptScore W2080990079C544153396 @default.
- W2080990079 hasConceptScore W2080990079C55493867 @default.
- W2080990079 hasConceptScore W2080990079C74998103 @default.
- W2080990079 hasConceptScore W2080990079C86803240 @default.
- W2080990079 hasIssue "4" @default.
- W2080990079 hasLocation W20809900791 @default.
- W2080990079 hasLocation W20809900792 @default.
- W2080990079 hasOpenAccess W2080990079 @default.
- W2080990079 hasPrimaryLocation W20809900791 @default.
- W2080990079 hasRelatedWork W1987782123 @default.
- W2080990079 hasRelatedWork W1999471762 @default.
- W2080990079 hasRelatedWork W2006793070 @default.
- W2080990079 hasRelatedWork W2015452657 @default.
- W2080990079 hasRelatedWork W2032990432 @default.
- W2080990079 hasRelatedWork W2034049967 @default.
- W2080990079 hasRelatedWork W2044864133 @default.
- W2080990079 hasRelatedWork W2069754293 @default.
- W2080990079 hasRelatedWork W2118148958 @default.
- W2080990079 hasRelatedWork W2239694384 @default.
- W2080990079 hasVolume "28" @default.
- W2080990079 isParatext "false" @default.
- W2080990079 isRetracted "false" @default.
- W2080990079 magId "2080990079" @default.
- W2080990079 workType "article" @default.