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- W2080991672 abstract "Penicillinase-deficient mutants were isolated from Kluyvera citrophila KY 3641 capable of carrying out enzymatic synthesis of 6-aminopenicillanic acid (6-APA) or D(-)-α-aminobenzy lpenicillin (APc). Acridine orange treatment was found effective for the isolation of such mutants, some of which could produce larger amounts of 6-APA or APc than the parent strain. Particularly during an earlier stage of growth, the penicillin acylase activity of these penicillinase-deficient mutants did emerge due to the absence of penicillinase, while that of the parent strain did not appear because of its penicillinase activity." @default.
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- W2080991672 date "1973-01-01" @default.
- W2080991672 modified "2023-10-03" @default.
- W2080991672 title "Isolation of Penicillinase-deficient Mutants of Kluyera citrophila KY 3641" @default.
- W2080991672 doi "https://doi.org/10.1271/bbb1961.37.335" @default.
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