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- W2080995768 abstract "induced by nuclear Hoechst staining or of DNA nicking as mea sured by TUNEL staining. We observed apoptotic cells in the dermal papilla with both Hoechst and TUNEL techniques. Staining for the anti-apoptotic protein Bcl-2 showed detectable levels of Bcl-2 in the dermal papilla of AA patients. These studies are preliminary indication that dermal papilla damage may be a critical component of alopecia areata, and that apoptosis is one endpoint observed. The presence of Bcl-2 in the same papilla indicates that an apoptosis may be induced in the presence of intact anti-apoptotic defenses. It must be noted that in hematopoietic and non-hematopoietic IMMUNOLOGIC CYTOTOXICITY IN ALOPECIA AREATA 9S" @default.
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- W2080995768 date "1995-05-01" @default.
- W2080995768 modified "2023-09-29" @default.
- W2080995768 title "Cytokines and Dermal Papilla Function in Alopecia Areata" @default.
- W2080995768 doi "https://doi.org/10.1038/jid.1995.32" @default.
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