Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081016672> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2081016672 endingPage "409" @default.
- W2081016672 startingPage "397" @default.
- W2081016672 abstract "On the basis of almost 15 years of experience with thiazide treatment in 346 patients with calcium stones, we believe that the following conclusions are justified: 1) Stone progression ceases in at least 90% of patients who take hydrochlorothiazide (50 mg, twice daily) on a regular basis. 2) A reduced dose of hydrochlorothiazide, i.e., 25 mg twice daily, appears to be effective in a significant proportion of patients. 3) Thiazides are effective in normocalciuric as well as hypercalciuric patients and in most patients with tubular ectasia (medullary sponge kidney). 4. Side effects necessitate discontinuation of thiazide treatment in approximately 7% of patients. The incidence and severity of side effects is reduced by initiating treatment with a small dose and by increasing the dose progressively until the full maintenance dose is achieved. A trial with a reduced dose is warranted in patients who are unable to tolerate the regular maintenance dose. 5) The therapeutic efficacy of thiazides in stone prevention cannot be accurately predicted by the degree of hypocalciuric response. Stone prevention may cease despite a minimal hypocalciuric response, whereas stone progression may occur when an adequate hypocalciuric response has taken place. 6) In addition to the hypocalciuric action, thiazides reduce urine oxalate excretion and increase urine zinc and (probably) magnesium; these effects probably contribute to the efficacy of this agent in stone prevention." @default.
- W2081016672 created "2016-06-24" @default.
- W2081016672 creator A5016670464 @default.
- W2081016672 creator A5057423217 @default.
- W2081016672 date "1978-05-01" @default.
- W2081016672 modified "2023-09-27" @default.
- W2081016672 title "Prevention of calcium stones with thiazides" @default.
- W2081016672 cites W101346608 @default.
- W2081016672 cites W1594209984 @default.
- W2081016672 cites W1969489133 @default.
- W2081016672 cites W2010785864 @default.
- W2081016672 cites W2010876504 @default.
- W2081016672 cites W2015310727 @default.
- W2081016672 cites W2015445040 @default.
- W2081016672 cites W2018309915 @default.
- W2081016672 cites W2026970130 @default.
- W2081016672 cites W2030139318 @default.
- W2081016672 cites W2032679375 @default.
- W2081016672 cites W2034873907 @default.
- W2081016672 cites W2035808075 @default.
- W2081016672 cites W2038296483 @default.
- W2081016672 cites W2042242853 @default.
- W2081016672 cites W2043493658 @default.
- W2081016672 cites W2060905935 @default.
- W2081016672 cites W2061480530 @default.
- W2081016672 cites W2064236437 @default.
- W2081016672 cites W2072694875 @default.
- W2081016672 cites W2074611198 @default.
- W2081016672 cites W2078888669 @default.
- W2081016672 cites W2082960373 @default.
- W2081016672 cites W2087449944 @default.
- W2081016672 cites W2154201916 @default.
- W2081016672 cites W2294201659 @default.
- W2081016672 cites W2331145586 @default.
- W2081016672 cites W2334809253 @default.
- W2081016672 cites W4254812746 @default.
- W2081016672 cites W4297571859 @default.
- W2081016672 cites W4298256422 @default.
- W2081016672 doi "https://doi.org/10.1038/ki.1978.58" @default.
- W2081016672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/351268" @default.
- W2081016672 hasPublicationYear "1978" @default.
- W2081016672 type Work @default.
- W2081016672 sameAs 2081016672 @default.
- W2081016672 citedByCount "265" @default.
- W2081016672 countsByYear W20810166722012 @default.
- W2081016672 countsByYear W20810166722013 @default.
- W2081016672 countsByYear W20810166722014 @default.
- W2081016672 countsByYear W20810166722015 @default.
- W2081016672 countsByYear W20810166722016 @default.
- W2081016672 countsByYear W20810166722017 @default.
- W2081016672 countsByYear W20810166722018 @default.
- W2081016672 countsByYear W20810166722021 @default.
- W2081016672 countsByYear W20810166722022 @default.
- W2081016672 countsByYear W20810166722023 @default.
- W2081016672 crossrefType "journal-article" @default.
- W2081016672 hasAuthorship W2081016672A5016670464 @default.
- W2081016672 hasAuthorship W2081016672A5057423217 @default.
- W2081016672 hasBestOaLocation W20810166721 @default.
- W2081016672 hasConcept C126322002 @default.
- W2081016672 hasConcept C126894567 @default.
- W2081016672 hasConcept C2778715236 @default.
- W2081016672 hasConcept C2779403450 @default.
- W2081016672 hasConcept C2779918671 @default.
- W2081016672 hasConcept C2780361556 @default.
- W2081016672 hasConcept C2780437262 @default.
- W2081016672 hasConcept C71924100 @default.
- W2081016672 hasConcept C84393581 @default.
- W2081016672 hasConceptScore W2081016672C126322002 @default.
- W2081016672 hasConceptScore W2081016672C126894567 @default.
- W2081016672 hasConceptScore W2081016672C2778715236 @default.
- W2081016672 hasConceptScore W2081016672C2779403450 @default.
- W2081016672 hasConceptScore W2081016672C2779918671 @default.
- W2081016672 hasConceptScore W2081016672C2780361556 @default.
- W2081016672 hasConceptScore W2081016672C2780437262 @default.
- W2081016672 hasConceptScore W2081016672C71924100 @default.
- W2081016672 hasConceptScore W2081016672C84393581 @default.
- W2081016672 hasIssue "5" @default.
- W2081016672 hasLocation W20810166721 @default.
- W2081016672 hasLocation W20810166722 @default.
- W2081016672 hasOpenAccess W2081016672 @default.
- W2081016672 hasPrimaryLocation W20810166721 @default.
- W2081016672 hasRelatedWork W1917067027 @default.
- W2081016672 hasRelatedWork W2043010698 @default.
- W2081016672 hasRelatedWork W2075781861 @default.
- W2081016672 hasRelatedWork W2108336570 @default.
- W2081016672 hasRelatedWork W2110505685 @default.
- W2081016672 hasRelatedWork W2395279189 @default.
- W2081016672 hasRelatedWork W2412965776 @default.
- W2081016672 hasRelatedWork W2416517583 @default.
- W2081016672 hasRelatedWork W2475345624 @default.
- W2081016672 hasRelatedWork W2884626812 @default.
- W2081016672 hasVolume "13" @default.
- W2081016672 isParatext "false" @default.
- W2081016672 isRetracted "false" @default.
- W2081016672 magId "2081016672" @default.
- W2081016672 workType "article" @default.