FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081036686> ?p ?o ?g. }

• W2081036686 endingPage "2736" @default.
• W2081036686 startingPage "2726" @default.
• W2081036686 abstract "MHC class II heterozygotes form haplotype-mismatched heterodimers (combining α and β chains of different alleles). Transfected L-cells expressing AαdAβd or AαdAβb presented exogenous OVA(323–339) peptide to T cells with similar high efficiency, while AαbAβb was less efficient and AαbAβd was ineffective. In contrast, AαdAβb greatly exceeded AαdAβd in processing of intact OVA for presentation of OVA(323–339); AαbAβb was even less efficient and AαbAβd was ineffective. Of macrophages from C57BL/6 (H-2b), DBA/2 (H-2d) and B6D2F1 (H-2b×d)mice, B6D2F1 macrophages had highest I-A expression and efficiency for OVA processing or presentation of exogenous OVA(323–339) peptide. Blocking antibodies specific for I-A chains showed that OVA processing by B6D2F1 macrophages primarily involved haplotype-mismatched AαdAβb heterodimers, whereas AαdAβd and AαbAβb contributed more to presentation of exogenous OVA(323–339) peptide. OVA(323–339):I-A complexes were formed from OVA within 10 min with B6D2F1 macrophages but not until 20 min with C57BL/6 or DBA/2 macrophages, and OVA processing was more resistant to inhibition of late endocytic function by hypothermia (18°C) in B6D2F1 than C57BL/6 or DBA/2 macrophages. These results indicate that AαdAβb haplotype-mismatched heterodimers may contribute to antigen processing in early endocytic compartments." @default.
• W2081036686 created "2016-06-24" @default.
• W2081036686 creator A5050014544 @default.
• W2081036686 creator A5055729386 @default.
• W2081036686 date "2002-10-01" @default.
• W2081036686 modified "2023-10-14" @default.
• W2081036686 title "Differences in antigen processing with haplotype-mismatched MHC class II heterodimers: AαdAβb heterodimers participate in early endosomal processing" @default.
• W2081036686 cites W113162970 @default.
• W2081036686 cites W1540025977 @default.
• W2081036686 cites W1553916036 @default.
• W2081036686 cites W1555760151 @default.
• W2081036686 cites W1557086683 @default.
• W2081036686 cites W1963584953 @default.
• W2081036686 cites W1974603911 @default.
• W2081036686 cites W1984288819 @default.
• W2081036686 cites W1994841263 @default.
• W2081036686 cites W2012952808 @default.
• W2081036686 cites W2015611329 @default.
• W2081036686 cites W2017936764 @default.
• W2081036686 cites W2020029625 @default.
• W2081036686 cites W2027753643 @default.
• W2081036686 cites W2030238175 @default.
• W2081036686 cites W2033893498 @default.
• W2081036686 cites W2033950321 @default.
• W2081036686 cites W2040914101 @default.
• W2081036686 cites W2044243024 @default.
• W2081036686 cites W2046328222 @default.
• W2081036686 cites W2047122601 @default.
• W2081036686 cites W2051655066 @default.
• W2081036686 cites W2069831383 @default.
• W2081036686 cites W2072541124 @default.
• W2081036686 cites W2081123727 @default.
• W2081036686 cites W2083046120 @default.
• W2081036686 cites W2084012186 @default.
• W2081036686 cites W2093820883 @default.
• W2081036686 cites W2095352046 @default.
• W2081036686 cites W2096212030 @default.
• W2081036686 cites W2105270641 @default.
• W2081036686 cites W2113618503 @default.
• W2081036686 cites W2145986415 @default.
• W2081036686 cites W2154190862 @default.
• W2081036686 cites W2165495862 @default.
• W2081036686 cites W2168733023 @default.
• W2081036686 cites W952001987 @default.
• W2081036686 cites W2094223030 @default.
• W2081036686 doi "https://doi.org/10.1002/1521-4141(2002010)32:10<2726::aid-immu2726>3.0.co;2-8" @default.
• W2081036686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12355424" @default.
• W2081036686 hasPublicationYear "2002" @default.
• W2081036686 type Work @default.
• W2081036686 sameAs 2081036686 @default.
• W2081036686 citedByCount "2" @default.
• W2081036686 countsByYear W20810366862022 @default.
• W2081036686 countsByYear W20810366862023 @default.
• W2081036686 crossrefType "journal-article" @default.
• W2081036686 hasAuthorship W2081036686A5050014544 @default.
• W2081036686 hasAuthorship W2081036686A5055729386 @default.
• W2081036686 hasConcept C102747710 @default.
• W2081036686 hasConcept C104317684 @default.
• W2081036686 hasConcept C108249834 @default.
• W2081036686 hasConcept C147483822 @default.
• W2081036686 hasConcept C1491633281 @default.
• W2081036686 hasConcept C153911025 @default.
• W2081036686 hasConcept C170627219 @default.
• W2081036686 hasConcept C180754005 @default.
• W2081036686 hasConcept C197754878 @default.
• W2081036686 hasConcept C203014093 @default.
• W2081036686 hasConcept C207936829 @default.
• W2081036686 hasConcept C2776090121 @default.
• W2081036686 hasConcept C2778814158 @default.
• W2081036686 hasConcept C28005876 @default.
• W2081036686 hasConcept C55493867 @default.
• W2081036686 hasConcept C79747257 @default.
• W2081036686 hasConcept C79879829 @default.
• W2081036686 hasConcept C83464605 @default.
• W2081036686 hasConcept C86803240 @default.
• W2081036686 hasConcept C8891405 @default.
• W2081036686 hasConcept C95444343 @default.
• W2081036686 hasConceptScore W2081036686C102747710 @default.
• W2081036686 hasConceptScore W2081036686C104317684 @default.
• W2081036686 hasConceptScore W2081036686C108249834 @default.
• W2081036686 hasConceptScore W2081036686C147483822 @default.
• W2081036686 hasConceptScore W2081036686C1491633281 @default.
• W2081036686 hasConceptScore W2081036686C153911025 @default.
• W2081036686 hasConceptScore W2081036686C170627219 @default.
• W2081036686 hasConceptScore W2081036686C180754005 @default.
• W2081036686 hasConceptScore W2081036686C197754878 @default.
• W2081036686 hasConceptScore W2081036686C203014093 @default.
• W2081036686 hasConceptScore W2081036686C207936829 @default.
• W2081036686 hasConceptScore W2081036686C2776090121 @default.
• W2081036686 hasConceptScore W2081036686C2778814158 @default.
• W2081036686 hasConceptScore W2081036686C28005876 @default.
• W2081036686 hasConceptScore W2081036686C55493867 @default.
• W2081036686 hasConceptScore W2081036686C79747257 @default.
• W2081036686 hasConceptScore W2081036686C79879829 @default.
• W2081036686 hasConceptScore W2081036686C83464605 @default.
• W2081036686 hasConceptScore W2081036686C86803240 @default.
• W2081036686 hasConceptScore W2081036686C8891405 @default.
• W2081036686 hasConceptScore W2081036686C95444343 @default.

• next