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- W2081043887 abstract "We estimated the frequencies of GSTM1 and GSTT1 null homozygotes in 10 different ethnic populations of India by a genotyping method based on polymerase chain reaction. These populations, inhabiting diverse geographical locations and occupying various positions in the sociocultural hierarchy, were represented by a sample of 299 unrelated individuals. Frequencies of GSTM1 and GSTT1 null homozygotes varied from 20% to 79% and 3% to 39%, respectively, across the study populations. Maximum frequencies of GSTM1 and GSTT1 null homozygotes (79% and 39%, respectively) have been observed in the same population (Jamatia). Frequencies of homozygous null genotypes at the GSTM1 and GSTT1 loci show a significant positive correlation in these populations, which is contrary to expectations. A possible implication is that the two enzymes are working in tandem, instead of working in a complementary way." @default.
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- W2081043887 date "2001-01-01" @default.
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- W2081043887 title "Ethnic Differences in Distributions of GSTM1 and GSTT1 Homozygous "Null" Genotypes in India" @default.
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- W2081043887 doi "https://doi.org/10.1353/hub.2001.0040" @default.
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