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• W2081090151 abstract "Electrophysiologic studies were prospectively performed in 91 consecutive patients referred for evaluation of sustained ventricular tachycardia or sudden cardiac death. Fifty-two patients had a history of sustained ventricular tachycardia and 39 patients had a history of sudden cardiac death. The identical stimulation protocol was used in all patients. The stepwise protocol involved atrial pacing, burst ventricular pacing, single, double, and triple extrastimuli during ventricular pacing. Stimulation was performed at the right ventricular apex at two and five times diastolic threshold. Using this protocol, ventricular tachycardia was inducible in 48 (92%) of the 52 patients with a history of sustained ventricular tachycardia and in 28 (72%) of 39 patients with a history of sudden cardiac death (p < 0.02). The use of a third extrastimulus increased the yield of inducible ventricular tachycardia by 37% in patients with a history of sustained ventricular tachycardia and by 25% in patients with a history of sudden cardiac death. Stimulation at five times diastolic threshold and stimulation from the right ventricular outflow tract added a 15% increment in overall yield of inducible ventricular tachycardia in patients with a history of sustained ventricular tachycardia, and a 26% increment in yield in patients with a history of sudden cardiac death. Forty-four (92%) of the 48 inducible patients in the sustained ventricular tachycardia group had inducible monomorphic ventricular tachycardia as compared to 19 (68%) of 28 patients in the sudden cardiac death group (p < 0.02). The use of such a stimulation protocol with a hierarchy of intensity, which includes triple extrastimuli and stimulation at five times diastolic threshold, obviates the need for left ventricular stimulation in the majority of patients with previously documented sustained ventricular arrhythmias. This protocol appears to produce a low incidence of artifactual arrhythmias in patients with previously documented sustained ventricular tachycardia. The significance of inducible polymorphic ventricular tachycardia in sudden death survivors is uncertain." @default.
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• W2081090151 date "1985-09-01" @default.
• W2081090151 modified "2023-10-18" @default.
• W2081090151 title "Mode of stimulation versus response: Validation of a protocol for induction of ventricular tachycardia" @default.
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• W2081090151 doi "https://doi.org/10.1016/0002-8703(85)90088-2" @default.
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