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• W2081145473 abstract "The pathogenesis of hidradenitis suppurativa (HS) is still enigmatic, and a valid animal model for HS is currently not available. The recent discovery of γ-secretase mutations in a subpopulation of patients with HS suggested γ-secretase transgenic mice as a model for HS pathogenesis. However, the discrepancies between human HS and these mice are daunting. We critically review cases of animal HS and transgenic γ-secretase mouse models for HS and discuss the criteria which should be met for a representative pathogenic model." @default.
• W2081145473 created "2016-06-24" @default.
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• W2081145473 date "2012-01-01" @default.
• W2081145473 modified "2023-09-25" @default.
• W2081145473 title "Can Animal Skin Diseases or Current Transgenic Mice Serve as a Model for Hidradenitis Suppurativa?" @default.
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• W2081145473 doi "https://doi.org/10.1159/000339773" @default.
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