FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081154155> ?p ?o ?g. }

• W2081154155 endingPage "58" @default.
• W2081154155 startingPage "52" @default.
• W2081154155 abstract "This study was conducted to compare the efficacy of phenytoin, valproate and levetiracetam in patients with GCSE.This randomised controlled prospective study was conducted on 150 patients to compare the efficacy of phenytoin (n = 50), valproate (n = 50) and levetiracetam (n = 50) along with lorazepam in patients with GCSE. All recruited patients received i.v. lorazepam (0.1mg/kg) followed by one of the 3 AEDs viz. phenytoin (20 mg/kg), valproate (30 mg/kg), and levetiracetam (25 mg/kg). Those who remained uncontrolled with 1st AED, received the other two AEDs sequentially. Clinical, imaging, EEG, etiological factors were analysed. Predictors of poor seizure control and outcome at discharge and at one month follow-up were assessed.In the phenytoin subgroup, the seizures could be controlled in 34 (68%) with lorazepam+phenytoin infusion. In the valproate subgroup (n = 50), seizures could be controlled in 34 (68%) with lorazepam+valproate infusion. In the levetiracetam subgroup (n = 50), seizures could be controlled in 39 (78%) with lorazepam+levetiracetam infusion. There was no statistically significant difference between the subgroups (p = 0.44). Overall, following lorazepam and 1st AED, 107/150 (71.3%) were controlled; with addition of 2nd AED, 130/150 (86.7%) and by adding 3rd AED, 138/150 (92%) were controlled. Fifteen out of 110 (13.6%) expired within 1 month of SE: phenytoin-6; valproate-4; and levetiracetam-5. Interestingly, 3 patients in the levetiracetam had post-ictal psychosis.Phenytoin, valproate, and levetiracetam are safe and equally efficacious following lorazepam in GCSE. The choice of AEDs could be individualised based on co-morbidities. SE could be controlled in 92% of patients with AEDs only and anaesthetics were not required in them." @default.
• W2081154155 created "2016-06-24" @default.
• W2081154155 creator A5005085166 @default.
• W2081154155 creator A5034502348 @default.
• W2081154155 creator A5037283054 @default.
• W2081154155 creator A5045863251 @default.
• W2081154155 creator A5047386380 @default.
• W2081154155 creator A5057398774 @default.
• W2081154155 creator A5060133831 @default.
• W2081154155 creator A5065407425 @default.
• W2081154155 creator A5084676111 @default.
• W2081154155 date "2015-08-01" @default.
• W2081154155 modified "2023-09-26" @default.
• W2081154155 title "Management of generalised convulsive status epilepticus (SE): A prospective randomised controlled study of combined treatment with intravenous lorazepam with either phenytoin, sodium valproate or levetiracetam – Pilot study" @default.
• W2081154155 cites W1492512073 @default.
• W2081154155 cites W1925921463 @default.
• W2081154155 cites W1965361922 @default.
• W2081154155 cites W1986554310 @default.
• W2081154155 cites W1988358928 @default.
• W2081154155 cites W1994814319 @default.
• W2081154155 cites W1995803117 @default.
• W2081154155 cites W2019957633 @default.
• W2081154155 cites W2025067370 @default.
• W2081154155 cites W2036467957 @default.
• W2081154155 cites W2046409377 @default.
• W2081154155 cites W2070330802 @default.
• W2081154155 cites W2071725069 @default.
• W2081154155 cites W2074130919 @default.
• W2081154155 cites W2086981442 @default.
• W2081154155 cites W2091795656 @default.
• W2081154155 cites W2095474831 @default.
• W2081154155 cites W2111957903 @default.
• W2081154155 cites W2118126943 @default.
• W2081154155 cites W2125292090 @default.
• W2081154155 cites W2129658473 @default.
• W2081154155 cites W2134576429 @default.
• W2081154155 cites W2165926195 @default.
• W2081154155 cites W3020966147 @default.
• W2081154155 doi "https://doi.org/10.1016/j.eplepsyres.2015.04.013" @default.
• W2081154155 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26088885" @default.
• W2081154155 hasPublicationYear "2015" @default.
• W2081154155 type Work @default.
• W2081154155 sameAs 2081154155 @default.
• W2081154155 citedByCount "83" @default.
• W2081154155 countsByYear W20811541552015 @default.
• W2081154155 countsByYear W20811541552016 @default.
• W2081154155 countsByYear W20811541552017 @default.
• W2081154155 countsByYear W20811541552018 @default.
• W2081154155 countsByYear W20811541552019 @default.
• W2081154155 countsByYear W20811541552020 @default.
• W2081154155 countsByYear W20811541552021 @default.
• W2081154155 countsByYear W20811541552022 @default.
• W2081154155 countsByYear W20811541552023 @default.
• W2081154155 crossrefType "journal-article" @default.
• W2081154155 hasAuthorship W2081154155A5005085166 @default.
• W2081154155 hasAuthorship W2081154155A5034502348 @default.
• W2081154155 hasAuthorship W2081154155A5037283054 @default.
• W2081154155 hasAuthorship W2081154155A5045863251 @default.
• W2081154155 hasAuthorship W2081154155A5047386380 @default.
• W2081154155 hasAuthorship W2081154155A5057398774 @default.
• W2081154155 hasAuthorship W2081154155A5060133831 @default.
• W2081154155 hasAuthorship W2081154155A5065407425 @default.
• W2081154155 hasAuthorship W2081154155A5084676111 @default.
• W2081154155 hasConcept C118552586 @default.
• W2081154155 hasConcept C2775858608 @default.
• W2081154155 hasConcept C2777332695 @default.
• W2081154155 hasConcept C2777341932 @default.
• W2081154155 hasConcept C2778186239 @default.
• W2081154155 hasConcept C2778337148 @default.
• W2081154155 hasConcept C2779706987 @default.
• W2081154155 hasConcept C42219234 @default.
• W2081154155 hasConcept C71924100 @default.
• W2081154155 hasConceptScore W2081154155C118552586 @default.
• W2081154155 hasConceptScore W2081154155C2775858608 @default.
• W2081154155 hasConceptScore W2081154155C2777332695 @default.
• W2081154155 hasConceptScore W2081154155C2777341932 @default.
• W2081154155 hasConceptScore W2081154155C2778186239 @default.
• W2081154155 hasConceptScore W2081154155C2778337148 @default.
• W2081154155 hasConceptScore W2081154155C2779706987 @default.
• W2081154155 hasConceptScore W2081154155C42219234 @default.
• W2081154155 hasConceptScore W2081154155C71924100 @default.
• W2081154155 hasLocation W20811541551 @default.
• W2081154155 hasLocation W20811541552 @default.
• W2081154155 hasOpenAccess W2081154155 @default.
• W2081154155 hasPrimaryLocation W20811541551 @default.
• W2081154155 hasRelatedWork W1965016243 @default.
• W2081154155 hasRelatedWork W2000899854 @default.
• W2081154155 hasRelatedWork W2033857330 @default.
• W2081154155 hasRelatedWork W2051003362 @default.
• W2081154155 hasRelatedWork W2090551991 @default.
• W2081154155 hasRelatedWork W2090922081 @default.
• W2081154155 hasRelatedWork W2155924120 @default.
• W2081154155 hasRelatedWork W2610306386 @default.
• W2081154155 hasRelatedWork W2791789590 @default.
• W2081154155 hasRelatedWork W2607623777 @default.
• W2081154155 hasVolume "114" @default.
• W2081154155 isParatext "false" @default.
• W2081154155 isRetracted "false" @default.

• next