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• W2081169031 abstract "Abstract Further evidence is presented that the brain-specific protein S 100 is a constituent of the neuronal plasma membrane. This differentiation of the membrane is dependent on stimuli from the environment. Antiserum raised to S 100 was used in a micro-chamber to separate isolated nerve cells which had S 100 expressed on the surface. Micro-beads covered by antiserum to S 100 were used for localization and for cell separation. The S 100 function was studied by a new technique to test the effect of membrane S 100 protein in its calcium form on transport of GABA across freshly prepared nerve cell membranes from Deiters' neurons. Membrane S 100 stimulated such GABA transport up to 30% which was found by kinetic measurements and other tests to be an active transport. Glia as a thin layer covering the nerve cell membrane inhibit the stimulated GABA transport. The glia regulation of the S 100 protein's activity on the neuronal plasma membrane is discussed." @default.
• W2081169031 created "2016-06-24" @default.
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• W2081169031 date "1980-01-01" @default.
• W2081169031 modified "2023-09-27" @default.
• W2081169031 title "Membrane activity of a brain specific protein" @default.
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• W2081169031 doi "https://doi.org/10.1016/0305-0491(80)90329-6" @default.
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