Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081181859> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2081181859 endingPage "213" @default.
- W2081181859 startingPage "210" @default.
- W2081181859 abstract "OBJECTIVE: Inherited resistance to activated protein C, which is caused by a single factor V gene mutation, is a frequent risk factor for thrombosis. The purpose of this study was to determine the prevalence of activated protein C resistance in women with thromboembolic complications that had occured in connection with pregnancy or use of oral contraceptives. STUDY DESIGN: Activated protein C resistance was analyzed in women with previous thromboembolic complications in connection with pregnancy (n = 34) or oral contraceptives (n = 28), in healthy fertile women (n = 57), and in women during normal pregnancy (n = 18). Results of the activated protein C resistance test were expressed as activated protein C ratios, values <2 indicating activated protein C resistance. RESULTS: Activated protein C resistance was found in almost 60% of women with thromboembolic complications during pregnancy and in around 30% of women with thromboembolic complications during treatment with oral contraceptives. In nonpregnant controls approximately 10% had activated protein C resistance. In normal pregnancy activated protein C ratios were similar to those of normal controls. CONCLUSIONS: Activated protein C resistance, which is caused by a genetic defect in the factor V gene, was found to be highly prevalent in women with a history of thromboembolic complications during pregnancy. The gene defect is common in the general population, and the results evoke the question whether it would be reasonable to perform general screening for activated protein C resistance early during pregnancy or before prescription of oral contraceptives." @default.
- W2081181859 created "2016-06-24" @default.
- W2081181859 creator A5007302439 @default.
- W2081181859 creator A5059767907 @default.
- W2081181859 creator A5072063424 @default.
- W2081181859 date "1995-07-01" @default.
- W2081181859 modified "2023-10-18" @default.
- W2081181859 title "Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives" @default.
- W2081181859 cites W1558470276 @default.
- W2081181859 cites W157305924 @default.
- W2081181859 cites W1965958910 @default.
- W2081181859 cites W1970939717 @default.
- W2081181859 cites W2017967816 @default.
- W2081181859 cites W2036117417 @default.
- W2081181859 cites W2059308063 @default.
- W2081181859 cites W2065017742 @default.
- W2081181859 cites W2069343109 @default.
- W2081181859 cites W2077770912 @default.
- W2081181859 cites W2090368722 @default.
- W2081181859 cites W2105515856 @default.
- W2081181859 cites W2328547014 @default.
- W2081181859 cites W2412782517 @default.
- W2081181859 cites W2419569804 @default.
- W2081181859 cites W3115500913 @default.
- W2081181859 cites W3596876 @default.
- W2081181859 doi "https://doi.org/10.1016/0002-9378(95)90192-2" @default.
- W2081181859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7631684" @default.
- W2081181859 hasPublicationYear "1995" @default.
- W2081181859 type Work @default.
- W2081181859 sameAs 2081181859 @default.
- W2081181859 citedByCount "219" @default.
- W2081181859 countsByYear W20811818592012 @default.
- W2081181859 countsByYear W20811818592013 @default.
- W2081181859 countsByYear W20811818592014 @default.
- W2081181859 countsByYear W20811818592015 @default.
- W2081181859 countsByYear W20811818592016 @default.
- W2081181859 countsByYear W20811818592020 @default.
- W2081181859 crossrefType "journal-article" @default.
- W2081181859 hasAuthorship W2081181859A5007302439 @default.
- W2081181859 hasAuthorship W2081181859A5059767907 @default.
- W2081181859 hasAuthorship W2081181859A5072063424 @default.
- W2081181859 hasConcept C126322002 @default.
- W2081181859 hasConcept C131872663 @default.
- W2081181859 hasConcept C2776135265 @default.
- W2081181859 hasConcept C2777175894 @default.
- W2081181859 hasConcept C2779234561 @default.
- W2081181859 hasConcept C2779956388 @default.
- W2081181859 hasConcept C2780011451 @default.
- W2081181859 hasConcept C2780868729 @default.
- W2081181859 hasConcept C2781287897 @default.
- W2081181859 hasConcept C2908647359 @default.
- W2081181859 hasConcept C50440223 @default.
- W2081181859 hasConcept C54355233 @default.
- W2081181859 hasConcept C71924100 @default.
- W2081181859 hasConcept C86803240 @default.
- W2081181859 hasConcept C99454951 @default.
- W2081181859 hasConceptScore W2081181859C126322002 @default.
- W2081181859 hasConceptScore W2081181859C131872663 @default.
- W2081181859 hasConceptScore W2081181859C2776135265 @default.
- W2081181859 hasConceptScore W2081181859C2777175894 @default.
- W2081181859 hasConceptScore W2081181859C2779234561 @default.
- W2081181859 hasConceptScore W2081181859C2779956388 @default.
- W2081181859 hasConceptScore W2081181859C2780011451 @default.
- W2081181859 hasConceptScore W2081181859C2780868729 @default.
- W2081181859 hasConceptScore W2081181859C2781287897 @default.
- W2081181859 hasConceptScore W2081181859C2908647359 @default.
- W2081181859 hasConceptScore W2081181859C50440223 @default.
- W2081181859 hasConceptScore W2081181859C54355233 @default.
- W2081181859 hasConceptScore W2081181859C71924100 @default.
- W2081181859 hasConceptScore W2081181859C86803240 @default.
- W2081181859 hasConceptScore W2081181859C99454951 @default.
- W2081181859 hasIssue "1" @default.
- W2081181859 hasLocation W20811818591 @default.
- W2081181859 hasLocation W20811818592 @default.
- W2081181859 hasOpenAccess W2081181859 @default.
- W2081181859 hasPrimaryLocation W20811818591 @default.
- W2081181859 hasRelatedWork W1925220407 @default.
- W2081181859 hasRelatedWork W1991819107 @default.
- W2081181859 hasRelatedWork W2047054292 @default.
- W2081181859 hasRelatedWork W2056444462 @default.
- W2081181859 hasRelatedWork W2109654476 @default.
- W2081181859 hasRelatedWork W2401747304 @default.
- W2081181859 hasRelatedWork W2411298939 @default.
- W2081181859 hasRelatedWork W2461745222 @default.
- W2081181859 hasRelatedWork W2587926608 @default.
- W2081181859 hasRelatedWork W3029762577 @default.
- W2081181859 hasVolume "173" @default.
- W2081181859 isParatext "false" @default.
- W2081181859 isRetracted "false" @default.
- W2081181859 magId "2081181859" @default.
- W2081181859 workType "article" @default.