FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081277646> ?p ?o ?g. }

• W2081277646 abstract "Exploration of triclosan analogs has led to novel diaryl ureas with significant potency against in vitro cultures of drug-resistant and drug-sensitive strains of the human malaria parasite Plasmodium falciparum. Compound 18 demonstrated EC(50) values of 37 and 55 nM versus in vitro cultured parasite strains and promising in vivo efficacy in a Plasmodium berghei antimalarial mouse model, with >50% survival at day 31 post-treatment when administered subcutaneously at 256 mg/kg. This series of compounds provides a chemical scaffold of novel architecture, as validated by cheminformatics analysis, to pursue antimalarial drug discovery efforts." @default.
• W2081277646 created "2016-06-24" @default.
• W2081277646 creator A5011923551 @default.
• W2081277646 creator A5027226153 @default.
• W2081277646 creator A5037740459 @default.
• W2081277646 creator A5037794182 @default.
• W2081277646 creator A5044700909 @default.
• W2081277646 creator A5045029465 @default.
• W2081277646 creator A5054963112 @default.
• W2081277646 creator A5062257527 @default.
• W2081277646 creator A5064519786 @default.
• W2081277646 creator A5068174974 @default.
• W2081277646 creator A5071314941 @default.
• W2081277646 creator A5073973321 @default.
• W2081277646 creator A5076433879 @default.
• W2081277646 creator A5089811323 @default.
• W2081277646 date "2013-02-01" @default.
• W2081277646 modified "2023-09-26" @default.
• W2081277646 title "Novel diaryl ureas with efficacy in a mouse model of malaria" @default.
• W2081277646 cites W180766444 @default.
• W2081277646 cites W1965051659 @default.
• W2081277646 cites W1983330902 @default.
• W2081277646 cites W1988560024 @default.
• W2081277646 cites W1991463936 @default.
• W2081277646 cites W1993795323 @default.
• W2081277646 cites W2010387696 @default.
• W2081277646 cites W2028918918 @default.
• W2081277646 cites W2038413365 @default.
• W2081277646 cites W2040826364 @default.
• W2081277646 cites W2048080607 @default.
• W2081277646 cites W2056252656 @default.
• W2081277646 cites W2056940833 @default.
• W2081277646 cites W2063953766 @default.
• W2081277646 cites W2064987052 @default.
• W2081277646 cites W2065949404 @default.
• W2081277646 cites W2093712250 @default.
• W2081277646 cites W2096747748 @default.
• W2081277646 cites W2114589435 @default.
• W2081277646 cites W2132694815 @default.
• W2081277646 cites W2161311583 @default.
• W2081277646 cites W2168918061 @default.
• W2081277646 cites W2178752708 @default.
• W2081277646 cites W2344075384 @default.
• W2081277646 doi "https://doi.org/10.1016/j.bmcl.2012.12.022" @default.
• W2081277646 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3746744" @default.
• W2081277646 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23313245" @default.
• W2081277646 hasPublicationYear "2013" @default.
• W2081277646 type Work @default.
• W2081277646 sameAs 2081277646 @default.
• W2081277646 citedByCount "20" @default.
• W2081277646 countsByYear W20812776462013 @default.
• W2081277646 countsByYear W20812776462014 @default.
• W2081277646 countsByYear W20812776462015 @default.
• W2081277646 countsByYear W20812776462017 @default.
• W2081277646 countsByYear W20812776462018 @default.
• W2081277646 countsByYear W20812776462019 @default.
• W2081277646 countsByYear W20812776462020 @default.
• W2081277646 countsByYear W20812776462021 @default.
• W2081277646 countsByYear W20812776462022 @default.
• W2081277646 crossrefType "journal-article" @default.
• W2081277646 hasAuthorship W2081277646A5011923551 @default.
• W2081277646 hasAuthorship W2081277646A5027226153 @default.
• W2081277646 hasAuthorship W2081277646A5037740459 @default.
• W2081277646 hasAuthorship W2081277646A5037794182 @default.
• W2081277646 hasAuthorship W2081277646A5044700909 @default.
• W2081277646 hasAuthorship W2081277646A5045029465 @default.
• W2081277646 hasAuthorship W2081277646A5054963112 @default.
• W2081277646 hasAuthorship W2081277646A5062257527 @default.
• W2081277646 hasAuthorship W2081277646A5064519786 @default.
• W2081277646 hasAuthorship W2081277646A5068174974 @default.
• W2081277646 hasAuthorship W2081277646A5071314941 @default.
• W2081277646 hasAuthorship W2081277646A5073973321 @default.
• W2081277646 hasAuthorship W2081277646A5076433879 @default.
• W2081277646 hasAuthorship W2081277646A5089811323 @default.
• W2081277646 hasBestOaLocation W20812776462 @default.
• W2081277646 hasConcept C136764020 @default.
• W2081277646 hasConcept C147597530 @default.
• W2081277646 hasConcept C150903083 @default.
• W2081277646 hasConcept C185592680 @default.
• W2081277646 hasConcept C202751555 @default.
• W2081277646 hasConcept C203014093 @default.
• W2081277646 hasConcept C207001950 @default.
• W2081277646 hasConcept C2777237215 @default.
• W2081277646 hasConcept C2778048844 @default.
• W2081277646 hasConcept C2778371730 @default.
• W2081277646 hasConcept C2780035454 @default.
• W2081277646 hasConcept C41008148 @default.
• W2081277646 hasConcept C55493867 @default.
• W2081277646 hasConcept C57992300 @default.
• W2081277646 hasConcept C68762167 @default.
• W2081277646 hasConcept C71928629 @default.
• W2081277646 hasConcept C74187038 @default.
• W2081277646 hasConcept C86803240 @default.
• W2081277646 hasConcept C98274493 @default.
• W2081277646 hasConceptScore W2081277646C136764020 @default.
• W2081277646 hasConceptScore W2081277646C147597530 @default.
• W2081277646 hasConceptScore W2081277646C150903083 @default.
• W2081277646 hasConceptScore W2081277646C185592680 @default.
• W2081277646 hasConceptScore W2081277646C202751555 @default.
• W2081277646 hasConceptScore W2081277646C203014093 @default.

• next