FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081286552> ?p ?o ?g. }

• W2081286552 endingPage "254" @default.
• W2081286552 startingPage "238" @default.
• W2081286552 abstract "Immunohistochemical analysis of cyclin-dependent kinase inhibitor 1C (CDKN1C, p57, Kip2) expression and molecular genotyping accurately classify hydatidiform moles into complete and partial types and distinguish these from non-molar specimens. Characteristics of a prospective series of all potentially molar specimens encountered in a large gynecologic pathology practice are summarized. Initially, all specimens were subjected to both analyses; this was later modified to triage cases for genotyping based on p57 results: p57-negative cases diagnosed as complete hydatidiform moles without genotyping; all p57-positive cases genotyped. Of the 678 cases, 645 were definitively classified as complete hydatidiform mole (201), partial hydatidiform mole (158), non-molar (272), and androgenetic/biparental mosaic (14); 33 were unsatisfactory, complex, or problematic. Of the 201 complete hydatidiform moles, 104 were p57-negative androgenetic and an additional 95 were p57-negative (no genotyping), 1 was p57-positive (retained maternal chromosome 11) androgenetic, and 1 was p57-non-reactive androgenetic; 90 (85%) of the 106 genotyped complete hydatidiform moles were monospermic and 16 were dispermic. Of the 158 partial hydatidiform moles, 155 were diandric triploid, with 154 p57-positive, 1 p57-negative (loss of maternal chromosome 11), and 1 p57-non-reactive; 3 were triandric tetraploid, with 2 p57-positive and 1 p57-negative (loss of maternal chromosome 11). Of 155 diandric triploid partial hydatidiform moles, 153 (99%) were dispermic and 2 were monospermic. Of the 272 non-molar specimens, 259 were p57-positive biparental diploid, 5 were p57-positive digynic triploid, 2 were p57-negative biparental diploid (no morphological features of biparental hydatidiform mole), and 6 were p57-non-reactive biparental diploid. Of the 14 androgenetic/biparental mosaics with discordant p57 expression, 6 were uniformly mosaic and 8 had a p57-negative androgenetic molar component. p57 expression is highly correlated with genotyping, serves as a reliable marker for diagnosis of complete hydatidiform moles, and identifies androgenetic cell lines in mosaic conceptions. Cases with aberrant and discordant p57 expression can be correctly classified by genotyping." @default.
• W2081286552 created "2016-06-24" @default.
• W2081286552 creator A5000576696 @default.
• W2081286552 creator A5023062113 @default.
• W2081286552 creator A5027789575 @default.
• W2081286552 creator A5041625714 @default.
• W2081286552 creator A5054209430 @default.
• W2081286552 creator A5065322902 @default.
• W2081286552 creator A5078957672 @default.
• W2081286552 date "2014-02-01" @default.
• W2081286552 modified "2023-10-15" @default.
• W2081286552 title "Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping" @default.
• W2081286552 cites W1507354079 @default.
• W2081286552 cites W1971692161 @default.
• W2081286552 cites W1974175677 @default.
• W2081286552 cites W1974926045 @default.
• W2081286552 cites W1986067460 @default.
• W2081286552 cites W1987247462 @default.
• W2081286552 cites W1991469965 @default.
• W2081286552 cites W1993905876 @default.
• W2081286552 cites W1994176909 @default.
• W2081286552 cites W1995973983 @default.
• W2081286552 cites W1996887637 @default.
• W2081286552 cites W1998473540 @default.
• W2081286552 cites W2011503388 @default.
• W2081286552 cites W2036835673 @default.
• W2081286552 cites W2037290921 @default.
• W2081286552 cites W2038699818 @default.
• W2081286552 cites W2039546666 @default.
• W2081286552 cites W2044217484 @default.
• W2081286552 cites W2044240222 @default.
• W2081286552 cites W2045079824 @default.
• W2081286552 cites W2057470220 @default.
• W2081286552 cites W2061369574 @default.
• W2081286552 cites W2061934347 @default.
• W2081286552 cites W2062571119 @default.
• W2081286552 cites W2064824097 @default.
• W2081286552 cites W2073129338 @default.
• W2081286552 cites W2075865581 @default.
• W2081286552 cites W2077049491 @default.
• W2081286552 cites W2080556077 @default.
• W2081286552 cites W2081949887 @default.
• W2081286552 cites W2088954865 @default.
• W2081286552 cites W2093319390 @default.
• W2081286552 cites W2095009259 @default.
• W2081286552 cites W2102400711 @default.
• W2081286552 cites W2106572315 @default.
• W2081286552 cites W2108989136 @default.
• W2081286552 cites W2117678062 @default.
• W2081286552 cites W2121389328 @default.
• W2081286552 cites W2124427507 @default.
• W2081286552 cites W2134290984 @default.
• W2081286552 cites W2138787601 @default.
• W2081286552 cites W2140513934 @default.
• W2081286552 cites W2144623119 @default.
• W2081286552 cites W2147485903 @default.
• W2081286552 cites W2152318322 @default.
• W2081286552 cites W2154392397 @default.
• W2081286552 cites W2158743805 @default.
• W2081286552 cites W2158868889 @default.
• W2081286552 cites W2161105867 @default.
• W2081286552 cites W2162534617 @default.
• W2081286552 cites W2165507042 @default.
• W2081286552 cites W2168075167 @default.
• W2081286552 cites W2314509679 @default.
• W2081286552 cites W2316814070 @default.
• W2081286552 doi "https://doi.org/10.1038/modpathol.2013.143" @default.
• W2081286552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23887308" @default.
• W2081286552 hasPublicationYear "2014" @default.
• W2081286552 type Work @default.
• W2081286552 sameAs 2081286552 @default.
• W2081286552 citedByCount "96" @default.
• W2081286552 countsByYear W20812865522014 @default.
• W2081286552 countsByYear W20812865522015 @default.
• W2081286552 countsByYear W20812865522016 @default.
• W2081286552 countsByYear W20812865522017 @default.
• W2081286552 countsByYear W20812865522018 @default.
• W2081286552 countsByYear W20812865522019 @default.
• W2081286552 countsByYear W20812865522020 @default.
• W2081286552 countsByYear W20812865522021 @default.
• W2081286552 countsByYear W20812865522022 @default.
• W2081286552 countsByYear W20812865522023 @default.
• W2081286552 crossrefType "journal-article" @default.
• W2081286552 hasAuthorship W2081286552A5000576696 @default.
• W2081286552 hasAuthorship W2081286552A5023062113 @default.
• W2081286552 hasAuthorship W2081286552A5027789575 @default.
• W2081286552 hasAuthorship W2081286552A5041625714 @default.
• W2081286552 hasAuthorship W2081286552A5054209430 @default.
• W2081286552 hasAuthorship W2081286552A5065322902 @default.
• W2081286552 hasAuthorship W2081286552A5078957672 @default.
• W2081286552 hasBestOaLocation W20812865521 @default.
• W2081286552 hasConcept C104317684 @default.
• W2081286552 hasConcept C135763542 @default.
• W2081286552 hasConcept C142724271 @default.
• W2081286552 hasConcept C143191323 @default.
• W2081286552 hasConcept C172680121 @default.
• W2081286552 hasConcept C203014093 @default.
• W2081286552 hasConcept C204232928 @default.

• next