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- W2081352783 abstract "The black deposits remaining at the site of subconjunctival injections of adrenin consist of complex organic salts formed from the reduction of ferric chloride by the adrenin. Iron is dissolved from the hypodermic needles by the strongly acid “adrenalin hydrochloride,” and is present as small amounts of ferric chloride. This is immediately reprecipitated by the strong reducing action of adrenin. All samples of “adrenalin hydrochloride” were found to be strongly acid to litmus paper and to have a hydrogen-ion concentration in the vicinity of 5.6. More black deposit is formed when old needles are used because they contain a film of ferric oxide over their inner surface, which is more readily dissolved by the adrenin than is pure steel. In order to avoid these black iron deposits, platinum needles should be used which are completely insoluble and rust free. The use of subconjunctival cotton pledgets soaked in adrenin is also recommended. From the Howe Laboratory of Ophthalmology, Harvard University, and the Massachusetts Eye and Ear Infirmary. The black deposits remaining at the site of subconjunctival injections of adrenin consist of complex organic salts formed from the reduction of ferric chloride by the adrenin. Iron is dissolved from the hypodermic needles by the strongly acid “adrenalin hydrochloride,” and is present as small amounts of ferric chloride. This is immediately reprecipitated by the strong reducing action of adrenin. All samples of “adrenalin hydrochloride” were found to be strongly acid to litmus paper and to have a hydrogen-ion concentration in the vicinity of 5.6. More black deposit is formed when old needles are used because they contain a film of ferric oxide over their inner surface, which is more readily dissolved by the adrenin than is pure steel. In order to avoid these black iron deposits, platinum needles should be used which are completely insoluble and rust free. The use of subconjunctival cotton pledgets soaked in adrenin is also recommended. From the Howe Laboratory of Ophthalmology, Harvard University, and the Massachusetts Eye and Ear Infirmary." @default.
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- W2081352783 date "1934-09-01" @default.
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- W2081352783 title "Subconjunctival Iron Deposits After Adrenin Injections" @default.
- W2081352783 doi "https://doi.org/10.1016/s0002-9394(34)90600-0" @default.
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