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• W2081369892 abstract "The aim of this study was to investigate the protective effect of cordymin on diabetic osteopenia in alloxan-induced diabetic rats and the possible mechanisms involved. The diabetic rats received daily intraperitoneal injection with cordymin (20, 50, and 100 mg/kg/day) for 5 weeks. Cordymin could restore the circulating blood glucose, glycosylated hemoglobin (HbA1c), serum alkaline phosphatase (ALP), tartrate resistant acid phosphatase (TRAP), and insulin levels in a dose-dependent manner. Also, the treatment of diabetic rats with cordymin could partially reverse the β cells death and decrease the total antioxidant status (TAOS) in the diabetic rats. The results may directly and indirectly account for the possible mechanism of the beneficial effect of cordymin on diabetic osteopenia, which was confirmed with the increased bone mineral content (BMC) and bone mineral density (BMD) in diabetic rats (P < 0.05). All those findings indicate that cordymin may play a protective role in diabetic osteoporosis." @default.
• W2081369892 created "2016-06-24" @default.
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• W2081369892 date "2013-01-01" @default.
• W2081369892 modified "2023-09-28" @default.
• W2081369892 title "The Protective Effect of Cordymin, a Peptide Purified from the Medicinal Mushroom<i>Cordyceps sinensis</i>, on Diabetic Osteopenia in Alloxan-Induced Diabetic Rats" @default.
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• W2081369892 doi "https://doi.org/10.1155/2013/985636" @default.
• W2081369892 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3794654" @default.
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