Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081372011> ?p ?o ?g. }
- W2081372011 endingPage "366" @default.
- W2081372011 startingPage "359" @default.
- W2081372011 abstract "A pilot study was conducted of the biological characteristics of the leukemia cells of newly diagnosed patients with poor prognosis acute myelogenous leukemia (AML). This study included measurements of the pretherapy proliferative rate of the leukemia cells in vivo, assessment of differentiation in vivo during remission induction therapy, and the level of expression of the fms, myc, and IL1β genes in pretherapy leukemia cells. Short cell cycle times were characteristic of the best prognostic category and were associated with a rapid reduction in marrow leukemia cells in cytosine arabinoside (araC)-sensitive patients. Expression of c-fms was associated with rapid reduction in marrow leukemia cells during araC therapy and with a successful treatment outcome. Expression of the IL1β gene was associated with short remissions. These studies suggest that when compared to newly diagnosed standard prognosis AML, the leukemia of poor prognosis patients is more likely to exhibit long cell cycle times, low levels of fms expression, and is less likely to be associated with myeloid differentiation during remission induction therapy. © 1993 Wiley-Liss, Inc." @default.
- W2081372011 created "2016-06-24" @default.
- W2081372011 creator A5000544878 @default.
- W2081372011 creator A5000847240 @default.
- W2081372011 creator A5011160416 @default.
- W2081372011 creator A5020886116 @default.
- W2081372011 creator A5022030651 @default.
- W2081372011 creator A5035535476 @default.
- W2081372011 creator A5048395915 @default.
- W2081372011 creator A5065804627 @default.
- W2081372011 creator A5078530354 @default.
- W2081372011 creator A5087963156 @default.
- W2081372011 date "1993-04-01" @default.
- W2081372011 modified "2023-09-26" @default.
- W2081372011 title "Biological characteristics of newly diagnosed poor prognosis acute myelogenous leukemia" @default.
- W2081372011 cites W1809290747 @default.
- W2081372011 cites W1956730086 @default.
- W2081372011 cites W2007210793 @default.
- W2081372011 cites W2017886169 @default.
- W2081372011 cites W2033582017 @default.
- W2081372011 cites W2053086190 @default.
- W2081372011 cites W2063879198 @default.
- W2081372011 cites W2071982773 @default.
- W2081372011 cites W2076309085 @default.
- W2081372011 cites W2076607091 @default.
- W2081372011 cites W2079031490 @default.
- W2081372011 cites W2132027522 @default.
- W2081372011 cites W2140731869 @default.
- W2081372011 cites W2150113701 @default.
- W2081372011 cites W2153926668 @default.
- W2081372011 cites W2165846604 @default.
- W2081372011 cites W2292071378 @default.
- W2081372011 cites W2401351341 @default.
- W2081372011 cites W2402720811 @default.
- W2081372011 cites W2405878472 @default.
- W2081372011 cites W4247785268 @default.
- W2081372011 doi "https://doi.org/10.1002/ajh.2830420406" @default.
- W2081372011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8493986" @default.
- W2081372011 hasPublicationYear "1993" @default.
- W2081372011 type Work @default.
- W2081372011 sameAs 2081372011 @default.
- W2081372011 citedByCount "10" @default.
- W2081372011 crossrefType "journal-article" @default.
- W2081372011 hasAuthorship W2081372011A5000544878 @default.
- W2081372011 hasAuthorship W2081372011A5000847240 @default.
- W2081372011 hasAuthorship W2081372011A5011160416 @default.
- W2081372011 hasAuthorship W2081372011A5020886116 @default.
- W2081372011 hasAuthorship W2081372011A5022030651 @default.
- W2081372011 hasAuthorship W2081372011A5035535476 @default.
- W2081372011 hasAuthorship W2081372011A5048395915 @default.
- W2081372011 hasAuthorship W2081372011A5065804627 @default.
- W2081372011 hasAuthorship W2081372011A5078530354 @default.
- W2081372011 hasAuthorship W2081372011A5087963156 @default.
- W2081372011 hasConcept C126322002 @default.
- W2081372011 hasConcept C143998085 @default.
- W2081372011 hasConcept C150903083 @default.
- W2081372011 hasConcept C203014093 @default.
- W2081372011 hasConcept C207001950 @default.
- W2081372011 hasConcept C2776960273 @default.
- W2081372011 hasConcept C2778461978 @default.
- W2081372011 hasConcept C2778729363 @default.
- W2081372011 hasConcept C2779282312 @default.
- W2081372011 hasConcept C2780007613 @default.
- W2081372011 hasConcept C502942594 @default.
- W2081372011 hasConcept C71924100 @default.
- W2081372011 hasConcept C86803240 @default.
- W2081372011 hasConceptScore W2081372011C126322002 @default.
- W2081372011 hasConceptScore W2081372011C143998085 @default.
- W2081372011 hasConceptScore W2081372011C150903083 @default.
- W2081372011 hasConceptScore W2081372011C203014093 @default.
- W2081372011 hasConceptScore W2081372011C207001950 @default.
- W2081372011 hasConceptScore W2081372011C2776960273 @default.
- W2081372011 hasConceptScore W2081372011C2778461978 @default.
- W2081372011 hasConceptScore W2081372011C2778729363 @default.
- W2081372011 hasConceptScore W2081372011C2779282312 @default.
- W2081372011 hasConceptScore W2081372011C2780007613 @default.
- W2081372011 hasConceptScore W2081372011C502942594 @default.
- W2081372011 hasConceptScore W2081372011C71924100 @default.
- W2081372011 hasConceptScore W2081372011C86803240 @default.
- W2081372011 hasIssue "4" @default.
- W2081372011 hasLocation W20813720111 @default.
- W2081372011 hasLocation W20813720112 @default.
- W2081372011 hasOpenAccess W2081372011 @default.
- W2081372011 hasPrimaryLocation W20813720111 @default.
- W2081372011 hasRelatedWork W1974032072 @default.
- W2081372011 hasRelatedWork W1975473919 @default.
- W2081372011 hasRelatedWork W1998142511 @default.
- W2081372011 hasRelatedWork W2090016234 @default.
- W2081372011 hasRelatedWork W2430567572 @default.
- W2081372011 hasRelatedWork W2791968852 @default.
- W2081372011 hasRelatedWork W2909695583 @default.
- W2081372011 hasRelatedWork W3096003772 @default.
- W2081372011 hasRelatedWork W3207807551 @default.
- W2081372011 hasRelatedWork W42711520 @default.
- W2081372011 hasVolume "42" @default.
- W2081372011 isParatext "false" @default.
- W2081372011 isRetracted "false" @default.
- W2081372011 magId "2081372011" @default.