Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081390562> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2081390562 abstract "Abstract Antigens induce sensitized lymphocytes to undergo mitosis and to secrete soluble products, termed lymphokines, which modulate the immune response. Plant lectins are known to act as polyclonal lymphocyte mitogens and, in some cases, stimulate lymphocytes to produce lymphokines. In an effort to explore the relationship of specific cell surface glycoconjugates to the induction of mitosis and the production of lymphokine activities we have examined the ability of the mitogenic lectins, concanavalin A and Wistaria floribunda mitogen, and the nonmitogenic hemagglutinin from Wistaria floribunda seeds to stimulate the production of macrophage migration inhibition factor (MIF), macrophage chemotactic factor (CF), and lymphotoxin (LT). Concanavalin A causes lymphocytes to produce MIF and LT but no detectable CF activities. W. floribunda mitogen induces lymphocytes to produce soluble substances which exhibit all three lymphokine activities. The nonmitogenic W. floribunda agglutinin causes lymphocytes to produce MIF and CF but no observable LT activity. Within the sensitivity of the assays employed, the results indicate that mitogenesis is not a corequisite of the expression of either macrophage migration inhibition factor or lymphocyte-derived chemotactic factor but it may be associated with the induction of lymphotoxin. It is also apparent that the expression of each lymphokine activity is independent of the expression of the other lymphokines studied." @default.
- W2081390562 created "2016-06-24" @default.
- W2081390562 creator A5064571714 @default.
- W2081390562 creator A5076206733 @default.
- W2081390562 date "1980-05-01" @default.
- W2081390562 modified "2023-09-25" @default.
- W2081390562 title "Lectin induction of lymphokines in cultured murine leukocytes" @default.
- W2081390562 cites W1539061345 @default.
- W2081390562 cites W1543333226 @default.
- W2081390562 cites W1560923897 @default.
- W2081390562 cites W1657682914 @default.
- W2081390562 cites W1966526066 @default.
- W2081390562 cites W1967324685 @default.
- W2081390562 cites W1967468173 @default.
- W2081390562 cites W1967805511 @default.
- W2081390562 cites W1978544592 @default.
- W2081390562 cites W1993312566 @default.
- W2081390562 cites W2001590496 @default.
- W2081390562 cites W2020484744 @default.
- W2081390562 doi "https://doi.org/10.1016/0008-8749(80)90275-0" @default.
- W2081390562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6989511" @default.
- W2081390562 hasPublicationYear "1980" @default.
- W2081390562 type Work @default.
- W2081390562 sameAs 2081390562 @default.
- W2081390562 citedByCount "4" @default.
- W2081390562 countsByYear W20813905622012 @default.
- W2081390562 crossrefType "journal-article" @default.
- W2081390562 hasAuthorship W2081390562A5064571714 @default.
- W2081390562 hasAuthorship W2081390562A5076206733 @default.
- W2081390562 hasConcept C103813035 @default.
- W2081390562 hasConcept C153911025 @default.
- W2081390562 hasConcept C19869320 @default.
- W2081390562 hasConcept C202751555 @default.
- W2081390562 hasConcept C203014093 @default.
- W2081390562 hasConcept C2777371288 @default.
- W2081390562 hasConcept C2777761686 @default.
- W2081390562 hasConcept C49382859 @default.
- W2081390562 hasConcept C55493867 @default.
- W2081390562 hasConcept C61879462 @default.
- W2081390562 hasConcept C86803240 @default.
- W2081390562 hasConcept C8891405 @default.
- W2081390562 hasConcept C95444343 @default.
- W2081390562 hasConceptScore W2081390562C103813035 @default.
- W2081390562 hasConceptScore W2081390562C153911025 @default.
- W2081390562 hasConceptScore W2081390562C19869320 @default.
- W2081390562 hasConceptScore W2081390562C202751555 @default.
- W2081390562 hasConceptScore W2081390562C203014093 @default.
- W2081390562 hasConceptScore W2081390562C2777371288 @default.
- W2081390562 hasConceptScore W2081390562C2777761686 @default.
- W2081390562 hasConceptScore W2081390562C49382859 @default.
- W2081390562 hasConceptScore W2081390562C55493867 @default.
- W2081390562 hasConceptScore W2081390562C61879462 @default.
- W2081390562 hasConceptScore W2081390562C86803240 @default.
- W2081390562 hasConceptScore W2081390562C8891405 @default.
- W2081390562 hasConceptScore W2081390562C95444343 @default.
- W2081390562 hasLocation W20813905621 @default.
- W2081390562 hasLocation W20813905622 @default.
- W2081390562 hasOpenAccess W2081390562 @default.
- W2081390562 hasPrimaryLocation W20813905621 @default.
- W2081390562 hasRelatedWork W1496915062 @default.
- W2081390562 hasRelatedWork W2053478368 @default.
- W2081390562 hasRelatedWork W2175077154 @default.
- W2081390562 hasRelatedWork W2394850917 @default.
- W2081390562 hasRelatedWork W2395087307 @default.
- W2081390562 hasRelatedWork W2400102731 @default.
- W2081390562 hasRelatedWork W2494960740 @default.
- W2081390562 hasRelatedWork W2794965101 @default.
- W2081390562 hasRelatedWork W199157789 @default.
- W2081390562 hasRelatedWork W4290332711 @default.
- W2081390562 isParatext "false" @default.
- W2081390562 isRetracted "false" @default.
- W2081390562 magId "2081390562" @default.
- W2081390562 workType "article" @default.