Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081492017> ?p ?o ?g. }
- W2081492017 endingPage "40" @default.
- W2081492017 startingPage "34" @default.
- W2081492017 abstract "The development of the cerebral cortex requires large-scale movement of neurons from areas of proliferation to areas of differentiation and adult function in the cortex proper, and the patterns of this neuronal migration are surprisingly complex. The migration of neurons is affected by several naturally occurring genetic defects in humans and mice; identification of the genes responsible for some of these conditions has recently yielded new insights into the mechanisms that regulate migration. Other key genes have been identified via the creation of induced mutations that can also cause dramatic disorders of neuronal migration. However, our understanding of the physiological and biochemical links between these genes is still relatively spotty. A number of molecules have also been studied in mice (Reelin, mDab1, and the VLDL and ApoE2 receptors) that appear to represent part of a coherent signaling pathway that regulates migration, because multiple genes cause an indistinguishable phenotype when mutated. On the other hand, two human genes that cause lissencephaly (LIS1, DCX) encode proteins that have recently been implicated as regulators or microtubule dynamics. This article reviews some of the mutant phenotypes in light of the mechanisms of neuronal migration. MRDD Research Reviews 6:34-40, 2000." @default.
- W2081492017 created "2016-06-24" @default.
- W2081492017 creator A5009957197 @default.
- W2081492017 date "2000-01-01" @default.
- W2081492017 modified "2023-10-16" @default.
- W2081492017 title "Genetics of neuronal migration in the cerebral cortex" @default.
- W2081492017 cites W1483926871 @default.
- W2081492017 cites W1503126591 @default.
- W2081492017 cites W1530869325 @default.
- W2081492017 cites W1563009973 @default.
- W2081492017 cites W1580418835 @default.
- W2081492017 cites W1580707798 @default.
- W2081492017 cites W1611957532 @default.
- W2081492017 cites W1637051517 @default.
- W2081492017 cites W1660407665 @default.
- W2081492017 cites W1667992367 @default.
- W2081492017 cites W1767420210 @default.
- W2081492017 cites W1773629427 @default.
- W2081492017 cites W1796084599 @default.
- W2081492017 cites W1827818423 @default.
- W2081492017 cites W1905265488 @default.
- W2081492017 cites W1916653587 @default.
- W2081492017 cites W1958704447 @default.
- W2081492017 cites W1964790765 @default.
- W2081492017 cites W1966087966 @default.
- W2081492017 cites W1967533792 @default.
- W2081492017 cites W1969821622 @default.
- W2081492017 cites W1971305731 @default.
- W2081492017 cites W1972775580 @default.
- W2081492017 cites W1972998445 @default.
- W2081492017 cites W1973303770 @default.
- W2081492017 cites W1976084841 @default.
- W2081492017 cites W1976297953 @default.
- W2081492017 cites W1979060895 @default.
- W2081492017 cites W1979890518 @default.
- W2081492017 cites W1983795337 @default.
- W2081492017 cites W1984421966 @default.
- W2081492017 cites W1989169683 @default.
- W2081492017 cites W1992502425 @default.
- W2081492017 cites W1994406909 @default.
- W2081492017 cites W1997073575 @default.
- W2081492017 cites W2001281440 @default.
- W2081492017 cites W2005746771 @default.
- W2081492017 cites W2009204794 @default.
- W2081492017 cites W2010571954 @default.
- W2081492017 cites W2012810028 @default.
- W2081492017 cites W2014467217 @default.
- W2081492017 cites W2020880696 @default.
- W2081492017 cites W2021958350 @default.
- W2081492017 cites W2022888964 @default.
- W2081492017 cites W2023281151 @default.
- W2081492017 cites W2030718949 @default.
- W2081492017 cites W2031050895 @default.
- W2081492017 cites W2035771357 @default.
- W2081492017 cites W2036337207 @default.
- W2081492017 cites W2036838270 @default.
- W2081492017 cites W2038901745 @default.
- W2081492017 cites W2039895922 @default.
- W2081492017 cites W2043155070 @default.
- W2081492017 cites W2043204105 @default.
- W2081492017 cites W2046655629 @default.
- W2081492017 cites W2048490262 @default.
- W2081492017 cites W2058219169 @default.
- W2081492017 cites W2060924536 @default.
- W2081492017 cites W2061761105 @default.
- W2081492017 cites W2062414231 @default.
- W2081492017 cites W2063511140 @default.
- W2081492017 cites W2063620761 @default.
- W2081492017 cites W2064290796 @default.
- W2081492017 cites W2066713988 @default.
- W2081492017 cites W2071535176 @default.
- W2081492017 cites W2072654899 @default.
- W2081492017 cites W2073382375 @default.
- W2081492017 cites W2077576885 @default.
- W2081492017 cites W2077630079 @default.
- W2081492017 cites W2077844146 @default.
- W2081492017 cites W2079396188 @default.
- W2081492017 cites W2080306322 @default.
- W2081492017 cites W2080931209 @default.
- W2081492017 cites W2080990838 @default.
- W2081492017 cites W2081028995 @default.
- W2081492017 cites W2081182977 @default.
- W2081492017 cites W2081336704 @default.
- W2081492017 cites W2082942943 @default.
- W2081492017 cites W2087538693 @default.
- W2081492017 cites W2088693403 @default.
- W2081492017 cites W2088745158 @default.
- W2081492017 cites W2089377875 @default.
- W2081492017 cites W2095790288 @default.
- W2081492017 cites W2096369647 @default.
- W2081492017 cites W2098955633 @default.
- W2081492017 cites W2101801068 @default.
- W2081492017 cites W2102409931 @default.
- W2081492017 cites W2105361671 @default.
- W2081492017 cites W2105660819 @default.
- W2081492017 cites W2113438288 @default.
- W2081492017 cites W2113630941 @default.
- W2081492017 cites W2119766505 @default.